ALBERT

Description: This paper firstly introduces green governance into the empirical research of family firms. Due to the fact that family firms have their own particularity in the principal agent and also have a strong desire to preserve social emotional wealth, this paper deeply studies the driving influence of family control on the green governance of family firms, and analyzes the moderating effect based on the political connection of executives. Taking the 2015–2017 Chinese family-listed firms that released social responsibility reports as the research sample, we find that family control contributes to the improvement of corporate green governance in family firms. However, the political connection of the actual controller weakens the effect of family control on the green governance of family firms. In addition, this research is also carried out under different situations, such as at the regional level and individual level. The research helps family firms give full play to their own advantages, guide the green governance practice of family firms, and improve the level of green governance.

Description: Since 2007, heterogeneous, high-viscosity active bituminous formations have often occurred during the drilling process in Yadavaran oilfield (Iran), Halfaya oilfield (Iraq), and tar sands (Canada). The formation of bitumen exhibits plastic and creep properties, and its adhesion is strong, so drilling accidents are easily caused, such as adhering vibrating screen, drill pipe sticking, lost circulation, and even well abandonment. These complex problems cause huge economic losses. Solvents used to dissolve bitumen are a feasible technology to remove bitumen effectively. In order to solve this problem, we used crude bitumen samples from Halfaya oilfield to study the relation between the bitumen component and different solvents. In this study, the temperature, crude bitumen sample to solvent ratio, stirring rate, stirring time, and ultrasound time on bitumen recovery by toluene were investigated by a single factor experiment. The optimum process parameter for bitumen recovery was obtained. Toluene, n-heptane, tetrahydrofuran, cyclohexane, cyclopentane, ethyl acetate, and n-pentane were chosen as the solvents for single solvent extraction and composite solvent extraction. The bitumen recovery increased significantly with the use of a composite solvent compared to a single solvent. The composite solvent ratio was 1:1. The highest bitumen recovery was 98.9 wt% by toluene/cyclohexane composite solvent. The SARA (saturates, aromatics, resins, and asphaltenes) components of the bitumen were analyzed. The toluene showed the highest asphaltene content, while the n-alkanes showed the lowest asphaltene content. The higher the asphaltene content, the higher the bitumen recovery. The composite solvent obtained the highest asphaltene content and bitumen recovery. The viscosity of bitumen extraction by different solvents was measured. The lower the bitumen viscosity, the higher the bitumen recovery. The element analysis indicated the solvent’s ability to extract bitumen colloids with the C/H ratio. This study provides a reliable theoretical basis for the subsequent adoption of effective anti-bitumen polluted drilling fluid additives.

Description: The expression and function of miR‐488 in prostate cancer (PCa) are unclear. In this study, we found that miR‐488 expression is diminished in PCa. By directly targeting the 3′UTR of 6‐phosphofructo‐2‐kinase/fructose‐2,6‐bisphosphatase, isoform3 (PFKFB3) mRNA, miR‐488 downregulates the expression of PFKFB3 protein and thereby inhibits PCa cell proliferation and glycolysis. Prostate cancer (PCa) remains the second leading cause of cancer‐related death among men in the United States, and its molecular mechanism remains to be elucidated. Recent studies have suggested that microRNAs may play an important role in cancer development and progression. By analyzing the Gene Expression Omnibus dataset, we found lower expression for miR‐488 in PCa than in normal tissues. Moreover, CCK‐8, EdU, glucose uptake, and lactate secrete assays revealed that overexpression of miR‐488 in PCa cell lines PC3 and DU145 resulted in inhibition of proliferation and glycolysis. In contrast, downregulation of miR‐488 expression promoted proliferation and glycolysis in PCa cells. Using a bioinformatic approach and dual‐luciferase reporter assays, we identified 6‐phosphofructo‐2‐kinase/fructose‐2,6‐bisphosphatase, isoform3 (PFKFB3), as a direct target of miR‐488. Inhibition of PFKFB3 also suppressed PCa cell glycolysis and proliferation. Our study suggests that miR‐488 inhibits PCa cell proliferation and glycolysis by targeting PFKFB3, and thus, miR‐488 may be a novel therapeutic candidate for PCa.

Description: Environmental problems caused by human behaviors have become increasingly serious in recent decades, thereby driving global green governance issue to become an important research agenda. The proper governance structure design and governance mechanism arrangement can effectively coordinate the relationship between human and nature. Literatures have provided mixed evidence of harmonious development of economy, society and environment. However, few studies have examined the balance of interests between human appeal and natural environment from the perspective of governance. Open innovation activities can effectively deal with the externalities of resources and environment and then relatively balance the economic value and green value of organizations, which is an effective green governance mode, reflecting the characteristics of the main subject composition and mechanism operation of green governance. This paper attempts to build a green governance framework for the cooperation based on sustainable development among enterprises, governments, social organizations, the public and the nature. This paper examines the synergy between human and nature by presenting a framework, including related theories of green governance, innovation subjects, innovation mechanisms and innovation mode. Each country and region could use the suggested framework to develop green governance guidelines that are suitable for the environmental carrying capacity of their own countries or regions. Enterprises could use the suggested framework to develop green development strategies to coordinate the economic values and green values.