ISSN:
1612-1112
Schlagwort(e):
Hormone-protein-binding
;
Oral contraceptures
;
Aqueous size exclusion high-performance
;
liquid chromatography
;
Immunoglobulins
;
Proteins separation
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Chemie und Pharmazie
Notizen:
Summary Immunoglobulins have been extracted from human and rabbit serum by size exclusion high performance liquid chromatography. In the case of rabbit immunized against ethinyl-oestradiol and woman having arterial thrombosis in the course of oral contraceptive use, the extracted immunoglobulins present a very high affinity for 17 β-oestradiol sulphate. The measurement of affinity to this compound of different extracted immunoglobulins allows a quantitative determination of these specific proteins. Comparative studies with radioimmunoassays are in good agreement.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF02258917
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