Publication Date:
2014-10-22
Description:
Zhang et al. (1) make a valuable contribution to the field of cancer metabolism, showing that the tumor suppressor p53 down-regulates the gluconeogenic key enzyme phosphoenolpyruvate carboxykinase (PEPCK, PCK1) via histone deacetylase sirtuin 6. The authors conclude that inhibition of gluconeogenesis may contribute to the tumor-suppressive function of p53. Gluconeogenesis,...
Keywords:
Letters
Print ISSN:
0027-8424
Electronic ISSN:
1091-6490
Topics:
Biology
,
Medicine
,
Natural Sciences in General
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