ISSN:
1365-2761
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Biology
,
Medicine
Notes:
Abstract. Twenty malignant lymphomas of northern pike, Esox lucius L., from the Baltic coast of Estonia were investigated immunohistochemically using rabbit anti-human polyclonal antibodies against lysozyme (LYS), alpha-1-antichymotrypsin (ACT) and S-100 protein. Based on the strongly positive reactions to LYS, ACT and S-100 found in a great number of histiocytes, two of these tumours were classified as histocytic diffuse malignant lymphomas. Furthermore, the weaker positive reaction to these antibodies detected in some of the histocytes in 10 other cases of diffuse malignant lymphoma indicates their histocytoid-lymphocytic origin. In addition, the lack of reaction to all antibodies used found in the remaining eight tumours, as well as their general morphological structure, allowed their diagnosis as lymphocytic diffuse malignant lymphomas. Thus, the immunohistochemical reactions to LYS, ACT and S-100 served as a tool for precisely distinguishing between the different types of lymphomas as well as for better understanding their origin.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1365-2761.1994.tb00254.x
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