ISSN:
1573-4978
Keywords:
Drosophila melanogaster
;
insertional mutation
;
P element
;
yellow locus
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract Large inserts have been found to appear within theyellow (y) locus of several unstable mutant lines derived from a parental strain (y 2 sc + w aG) ofDrosophila melanogaster. The inserts of the individual mutant lines correspond roughly to a series of multimers (4.1, 7.1, 14.3 and 28.9 kbp, respectively) and are always located at the same position, somewhat upstream of they gene transcription start site. Each of them begins and ends with a l-kbp sequence which shares restriction sites withP elements. One of these inserts (14.3 kbp) has been partially sequenced (1270 bp from the 5′ end). The first 1185 bp match exactly the sequence of an internally deletedP element. The remaining part of the sequence, on the other hand, is unrelated toP elements. It is assumed that large DNA sequences may be captured by the flankingP-element fragments and inserted into new chromosomal sites.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00996218
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