Publication Date:
2014-11-16
Description:
Article The presynaptic LAR-RPTPs interact with postsynaptic Slitrks and this contributes to regulating synapse formation. Here, the authors identified the minimal binding regions and determined the crystal structure of the resulting complex and performed functional analysis in cells to determine LAR-RPTP/Slitrk complex-mediated synapse formation. Nature Communications doi: 10.1038/ncomms6423 Authors: Ji Won Um, Kee Hun Kim, Beom Seok Park, Yeonsoo Choi, Doyoun Kim, Cha Yeon Kim, Soo Jin Kim, Minhye Kim, Ji Seung Ko, Seong-Gyu Lee, Gayoung Choii, Jungyong Nam, Won Do Heo, Eunjoon Kim, Jie-Oh Lee, Jaewon Ko, Ho Min Kim
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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