ISSN:
1573-8353
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract 4-Hydroxy- and 4-hydroxylamino-1-hydroxy-3-aryl-5,5-dimethyl-2-imidazolidinones, respectively, were obtained by treatment of N-arylcarbamoyl derivatives of N-(1-oximino-2-methyl-2-porpyl)hydroxylamine with acids and alkalis. 4-Hydroxylaminoimidazolidinones react with p-nitrobenzaldehyde to give nitrones and are converted in acidic media to 4-hydroxy derivatives, which by the action of methanol in the presence of p-toluenesulfonic acid give 4-methoxy-2-imidazolidinones. Acylation and alkylation of 4-hydroxy- and 4-methoxy-2-imidazolidinones take place at the hydroxy group attached to N(1).
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00480403
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