Publication Date:
2014-05-15
Description:
Article Paclitaxel is effective in the treatment of breast cancer but predicting which patients might respond to this drug is of clinical importance. Here, Jiang et al. show that germline mutations in TEKT4 , a protein that associates with microtubules, are associated with resistance to paclitaxel therapy. Nature Communications doi: 10.1038/ncomms4802 Authors: Yi-Zhou Jiang, Ke-Da Yu, Wen-Ting Peng, Gen-Hong Di, Jiong Wu, Guang-Yu Liu, Zhi-Ming Shao
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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