ALBERT

Description: This study investigated the heat-induced acceleration of cement hydration and pozzolanic reaction focusing on mechanical performance and structural modification at the meso- and micro-scale. The pozzolanic reaction was implemented by substituting 20 wt.% of cement with silica fume, considered the typical dosage of silica fume in ultra-high performance concrete. By actively consuming a limited amount of water and outer-formed portlandite on the unreacted cement grains, it was confirmed that high-temperature curing greatly enhances the pozzolanic reaction when compared with cement hydration under the same environment. The rate of strength development from the dual reactions of cement hydration and pozzolanic reaction was increased. After the high-temperature curing, further strength development was negligible because of the limited space availability and preconsumption of water under a low water-to-cement environment. Since the pozzolanic reaction does not directly require the anhydrous cement, the reaction can be more easily accelerated under restrained conditions because it does not heavily rely on the diffusion of the limited amount of water. Therefore, it significantly increases the mean chain length of the C–S–H, the size of C–S–H globules with a higher surface fractal dimension. This finding will be helpful in understanding the complicated hydration mechanism of high-strength concrete or ultra-high performance concrete, which has a very low water-to-cement ratio.

Description: Saponins in the Camellia sinensis seeds have a broad spectrum of biological properties and application potentials. However, up to now, no chromatographic methods have been developed to provide full fingerprinting and quality assurance for these saponins. This research aimed to develop a novel method to tentatively identify and quantify saponins in C. sinensis seeds by ultra-high-performance liquid chromatography coupled with photo-diode array detector and quadrupole time-of-flight mass spectrometry (UPLC-PDA-QTOF-MS/MS), and compare it with the classic vanillin-sulfuric acid assay. Fifty-one triterpene saponins, including six potentially new compounds, were simultaneously detected by UPLC-PDA-MS/MS, and their chemical structures were speculated according to the retention behavior and fragmentation pattern. The total saponin content in the crude extract and the purified saponin fraction of C. sinensis seeds were quantified to be 19.57 ± 0.05% (wt %) and 41.68 ± 0.09% (wt %) respectively by UPLC-PDA at 210 nm, while the corresponding values were determined to be 43.11 ± 3.17% (wt %) and 56.60 ± 5.79% (wt %) respectively by the vanillin-sulfuric acid assay. The developed UPLC-PDA -MS/MS method could determine specified saponins, and is more reliable for quantifying the C. sinensis seed saponins than the classic spectrophotometric method. It is of great significance for the future investigations and applications of these saponins.

Description: Theaflavins, the characteristic and bioactive polyphenols in black tea, possess the potential improving effects on insulin resistance-associated metabolic abnormalities, including obesity and type 2 diabetes mellitus. However, the related molecular mechanisms are still unclear. In this research, we investigated the protective effects of theaflavins against insulin resistance in HepG2 cells induced by palmitic acid. Theaflavins significantly increased glucose uptake of insulin-resistant cells at noncytotoxic doses. This activity was mediated by upregulating the total and membrane bound glucose transporter 4 protein expressions, increasing the phosphor-Akt (Ser473) level, and decreasing the phosphorylation of IRS-1 at Ser307. Moreover, theaflavins were found to enhance the mitochondrial DNA copy number, down-regulate the PGC-1β mRNA level and increase the PRC mRNA expression. Mdivi-1, a selective mitochondrial division inhibitor, could attenuate TFs-induced promotion of glucose uptake in insulin-resistant HepG2 cells. Taken together, these results suggested that theaflavins could improve hepatocellular insulin resistance induced by free fatty acids, at least partly through promoting mitochondrial biogenesis. Theaflavins are promising functional food ingredients and medicines for improving insulin resistance-related disorders.

Description: This paper presents a scaled GaN-HEMT large-signal model based on EM simulation. A large-signal model of the 10-finger GaN-HEMT consists of a large-signal model of the two-finger GaN-HEMT and an equivalent circuit of the interconnection circuit. The equivalent circuit of the interconnection circuit was extracted according to the EM simulation results. The large-signal model for the two-finger device is based on the conventional Angelov channel current model. The large-signal model for the 10-finger device was verified through load-pull measurement. The 10-finger GaN-HEMT produced an output power of about 20 W for both simulation and load-pull measurements.

Description: This study explored the hydration reaction of ultra-high-performance concrete (UHPC) by using X-ray diffraction (XRD), nuclear magnetic resonance (NMR), and thermogravimetric analysis (TGA) as analysis methods. The partial- or no-known crystal structure (PONKCS) method was adopted to quantify the two main amorphous phases of silica fume and C-S-H; such quantification is critical for understanding the hydration reaction of UHPC. The measured compressive strength was explained well by the degree of hydration found by the PONKCS method, particularly the amount of amorphous C-S-H. During heat treatment, the pozzolanic reaction was more intensified by efficiently consuming silica fume. After heat treatment, weak but continuous hydration was observed, in which the cement hydration reaction was dominant. Furthermore, the study discussed some limitations of using the PONKCS method for studying the complicated hydration assemblage of UHPC based on the results of TGA and NMR. Generally, the PONKCS method underestimated the content of silica fume in the early age of heat treatment. Furthermore, the structural evolution of C-S-H, confirmed by NMR, should be considered for more accurate quantification of C-S-H formed in UHPC. Nevertheless, PONKCS-based XRD could be useful for understanding and optimizing the material properties of UHPC undergoing heat treatment.

Description: This study investigated the material properties and hydration characteristics of calcium sulfoaluminate cement (CSA) based mortars cured under 3 different initial curing temperatures. Two CSA cements with different M-values were selected. Obtained experimental results of mechanical properties, dimensional stability, and heat release were explained by hydration characteristics from X-ray diffraction, thermal gravimetric analysis, porosimetry, and thermodynamic modeling. Decomposition of ettringite decreased compressive strength but re-formation of ettringite after additional curing at 30 °C helped to recover the strength in CSA cement with a high amount of calcium sulfate. CSA cement with a low amount of calcium sulfate which was designed to predominantly have monosulfate as the main hydration product, showed increased 1-day strength after higher temperature curing but this occurred was at the expense of decreased 28-day strength.