ISSN:
1662-0356
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Natural Sciences in General
,
Technology
Notes:
DNA has been recently used to construct a variety of nanoscale machines and switches,among them devices which can translocate, compute, or bind and release molecules. For futureapplications it is interesting to investigate whether these "artificial" functions can also beimplemented in vivo. As one step towards in vivo applications, we currently utilize RNA moleculesfor construction or control of molecular devices. RNA molecules can be transcribed from "artificialgenes" and either fold into functional nanoassemblies themselves or drive other nucleic acid-baseddevices as a "fuel". Furthermore, coupling of nanomachines to RNA transcription enables control oftheir behavior using gene regulatory motifs
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/42/transtech_doi~10.4028%252Fwww.scientific.net%252FAST.58.120.pdf
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