ISSN:
1432-119X
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary In this light microscopic study, the inhibitory effect of levamisole on the alkaline phosphatase of equine, bovine and rat neutrophilic leukocytes was examined histochemically, using 0.05, 0.1 and 0.5 mM levamisole in the incubation mixture. Levamisole proved to be a potent inhibitor of neutrophilic alkaline phosphatase already at very low concentrations. Statistically significant differences in the rate of inhibition of the enzyme were found between the species examined. Some observations of the eosinophils were also made; equine eosinophils were found to be considerably resistant towards alkaline phosphatase inhibition with levamisole at the concentrations used.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00492628
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