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  • 1
    Series available for loan
    Series available for loan
    Ueber die Functionaldeterminanten (1896)
    Leipzig : Engelmann
    Associated volumes
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    Call number: SR 90.0942(78)
    In: Ostwalds Klassiker der exakten Wissenschaften
    Type of Medium: Series available for loan
    Pages: 72 S.
    Series Statement: Ostwalds Klassiker der exakten Wissenschaften 78
    Language: German
    Location: Magazine - must be ordered
    Branch Library: GFZ Library
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  • 2
    Series available for loan
    Series available for loan
    Ueber die Bildung und die Eigenschaften der Determinanten (1896)
    Leipzig : Engelmann
    Associated volumes
    Details Availability
    Call number: SR 90.0942(77)
    In: Ostwalds Klassiker der exakten Wissenschaften
    Type of Medium: Series available for loan
    Pages: 73 S.
    Series Statement: Ostwalds Klassiker der exakten Wissenschaften 77
    Language: German
    Location: Magazine - must be ordered
    Branch Library: GFZ Library
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  • 3
    Electronic Resource
    Electronic Resource
    In vitro and in vivo expression studies of yopE from Yersinia enterocolitica using the gfp reporter gene (1998)
    Oxford BSL : Blackwell Publishing Ltd
    Molecular microbiology 30 (1998), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The Yersinia outer protein YopE belongs to the translocated effector proteins of pathogenic yersiniae. We constructed various truncated yopE genes fused to gfp (encoding the green fluorescent protein) to study yopE gene expression and YopE–GFP translocation of Y. enterocolitica in cell culture and mouse infection models. The hybrid gene fusions were co-expressed in Y. enterocolitica (i) on a low-copy plasmid in the presence of the virulence plasmid pYV08 (in trans configuration) and (ii) after co-integration by homologous recombination of a yopE–gfp-carrying suicide plasmid into pYV08 (co-integrate configuration). After 30 min of infection of HEp-2 cell monolayers, extracellularly located yersiniae began to emit green fluorescence after excitation. In contrast, internalized bacteria were weakly fluorescent. Translocation of YopE–GFP into HEp-2 cells by attached yersiniae was visualized by optical sectioning of fluorescent HEp-2 cells using confocal laser scanning microscopy and was confirmed by immunoprecipitation of cytosolic YopE–GFP from selectively solubilized HEp-2 cells. The co-translocation of other Yops was not significantly impaired by YopE–GFP as shown by YopH/YopE-mediated suppression of the oxidative burst of infected neutrophils. The time course of yopE–gfp expression (in trans as well as in the co-integrate configuration) in the HEp-2 cell infection model as well as after in vitro induction was studied using a highly sensitive CCD camera and a flow cytometer. Similar results were obtained with a YopE–LUC (firefly luciferase) protein fusion as reporter. After intraperitoneal, intravenous and orogastrical infection of Balb/c mice with the recombinant yersiniae strains, green fluorescing bacteria could be visualized microscopically in the peritoneum, the spleen, the liver and in the Peyer's patches. However, only weakly fluorescent yersiniae were observed in the intestinal lumen. These results were quantified by flow cytometric measurements. The application of gfp as a reporter gene turned out to be promising for the study of protein translocation by protein type III secretion systems and differential virulence gene expression in vivo.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2958.1998.01128.x
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  • 4
    Electronic Resource
    Electronic Resource
    Bile salts-, lysolecithin- and saponin-induced potentiation of phospholipase a hemolysis
    Amsterdam : Elsevier
    FEBS Letters 23 (1972), S. 61-64 
    Details
    ISSN: 0014-5793
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(72)80285-0
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  • 5
    Electronic Resource
    Electronic Resource
    On the solar cycle dependence of winds and planetary waves as seen from mid-latitude D1 LF mesopause region wind measurements (1998)
    Springer
    Annales geophysicae 16 (1998), S. 1534-1543 
    Details
    ISSN: 0992-7689
    Keywords: Meteorology and atmospheric dynamics ; Middle atmosphere dynamics Multiple regression analysis Quasi-2-day wave
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract At the Collm Observatory of the University of Leipzig LF D1 low-frequency total reflection nighttime wind measurements have been carried out continuously for more than two decades. Using a multiple regression analysis to derive prevailing winds, tides and the quasi-2-day wave from the half-hourly mean values of the horizontal wind components, monthly mean values of mesopause wind parameters are obtained that can be analysed with respect to long-term trends and influences of solar variability. The response of the prevailing wind to the 11-year solar cycle differs throughout the year. While in winter no significant correlation between the zonal prevailing wind and solar activity is found, in spring and summer a negative correlation between the TWC can be seen from the measurements. This is connected with stronger vertical gradients of the zonal prevailing wind during solar maximum than during solar minimum. Since the amplitude of the quasi-2-day wave is dependent on the zonal mean wind vertical gradient, this is connected with a positive correlation between solar activity and quasi-two-day wave activity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s00585-998-1534-3
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  • 6
    Electronic Resource
    Electronic Resource
    Growth and respiration during the larval development of Hyas coarctatus (Decapoda: Majidae) (1985)
    Springer
    Marine biology 87 (1985), S. 173-180 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The spider crab Hyas coarctatus Leach was reared in the laboratory from hatching to metamorphosis, and growth and respiration were measured in all larval stages at regular intervals of time. Growth, measured as dry weight (W), carbon (C), nitrogen (N), hydrogen (H), and energy (E; calculated from C), can be described in the zoeal stages by a power function, and as a non-linear (quadratic) regression equation of time (t; days) in the megalopa. C, H, and E showed higher growth rates than W or N during the zoeal stages, suggesting accumulation mainly of lipids rather than protein. Respiration (R; expressed as μg O2h-1 individual-1) increased as a linear function of t in the zoeal stages. From this simple relationship and the above power function for increase in W, equations describing the relationships between R and W and between QO 2 (μg O2h-1 mg-1), t, and W were derived for zoeal development. Both R and QO 2 first decreased during megalopa postmoult, then increased for a short period, before decreasing again toward metamorphosis. No descriptive models were proposed for these changes in the ultimate larval stage. The total amount of energy lost by zoeal respiration was less than their net gain by body growth, whereas the megalopa respired almost 14 times the amount of energy eventually gained. This means that net growth efficiency is far lower in the megalopa than in the zoeal stages of H. coarctatus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00539425
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  • 7
    Electronic Resource
    Electronic Resource
    Midlatitude Mesosphere/Lower Thermosphere Region Winds and Their Connection with European and Asian Tropospheric Parameters (2000)
    Springer
    Theoretical and applied climatology 65 (2000), S. 231-243 
    Details
    ISSN: 1434-4483
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Summary Investigation of long-term measurements of winter mesosphere/lower thermosphere (MLT) region zonal winds has shown a connection of northern hemisphere tropospheric parameters and MLT conditions. These are on one hand due to a connection of the stratospheric polar vortex and the North Atlantic Oscillation (NAO) and on the other hand forced by a coupling of the troposphere/lower stratosphere and the MLT region through planetary wave propagation and wave-mean flow interaction. The connection between European and Asian winter climatological parameters and the NAO leads to the fact, that the signal of Eurasian winter conditions can be found in the interannual variability of MLT winds. Some of these winter tropospheric parameters influence the strength of the Indian monsoon in the following summer, and this leads to a correlation between winter MLT winds and summer Indian rainfall, so that the midlatitude MLT winter dynamics can be used as a precursory signal of the strength of the Indian monsoon.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007040070046
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  • 8
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    Surface tension determines tissue shape and growth kinetics (2019)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2019
    Description: 〈p〉The collective self-organization of cells into three-dimensional structures can give rise to emergent physical properties such as fluid behavior. Here, we demonstrate that tissues growing on curved surfaces develop shapes with outer boundaries of constant mean curvature, similar to the energy minimizing forms of liquids wetting a surface. The amount of tissue formed depends on the shape of the substrate, with more tissue being deposited on highly concave surfaces, indicating a mechano-biological feedback mechanism. Inhibiting cell-contractility further revealed that active cellular forces are essential for generating sufficient surface stresses for the liquid-like behavior and growth of the tissue. This suggests that the mechanical signaling between cells and their physical environment, along with the continuous reorganization of cells and matrix is a key principle for the emergence of tissue shape.〈/p〉
    Electronic ISSN: 2375-2548
    Topics: Natural Sciences in General
    Published by American Association for the Advancement of Science (AAAS)
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  • 9
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    Verification of the mesospheric winds within the Canadian Middle Atmosphere Model Data Assimilation System using radar measurements (2011)
    Wiley
    Details
    Publication Date: 2011-08-19
    Description: In the standard version of Canadian Middle Atmosphere Model Data Assimilation System (CMAM-DAS), meteorological observations are assimilated only in the troposphere and stratosphere with no increments applied in the mesosphere. The mesospheric response is thus entirely due to internal model dynamics. This paper examines the influence of the assimilation of tropospheric and stratospheric observations upon the simulation of the mesospheric winds at middle and high northern latitudes in the CMAM-DAS. The modeled mesospheric horizontal winds are verified using radar observations. Results show that the CMAM-DAS can capture the variability of the observed tide-removed mean horizontal winds in the mesosphere, especially for the short-term variability during midwinter major sudden stratospheric warmings. This indicates that the mesospheric state is strongly constrained by the state of the lower atmosphere in the CMAM-DAS. This work provides further evidence for the coupling of the mesosphere with the lower atmosphere and demonstrates that the CMAM when constrained by tropospheric and stratospheric observations can provide a realistic description of mesospheric wind variability at middle and high northern latitudes, especially in winter. This is the first comprehensive report of comparison of CMAM-DAS analyses with radar measurements of tide-removed mean horizontal winds in the mesosphere.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 10
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    Mesospheric wind semidiurnal tides within the Canadian Middle Atmosphere Model Data Assimilation System (2011)
    Wiley
    Details
    Publication Date: 2011-09-02
    Description: The horizontal wind data from the standard version of Canadian Middle Atmosphere Model Data Assimilation System (CMAM-DAS) for the years 2006–2008 are analyzed to obtain the global structure and seasonal variability of the semidiurnal tide (SDT) in the mesosphere. The modeled amplitudes and phases of the SDTs at single stations from middle/high northern latitudes are quite similar to those observed by radars. The primary nonmigrating tides identified in both the meridional wind and zonal wind semidiurnal spectra at 88 km include the westward propagating wave numbers s = 1 (SW1), 3 (SW3), 4 (SW4), 6 (SW6), the standing s = 0 (S0), and the eastward propagating s = 2 (SE2). The migrating SDT (SW2) amplitude maxima usually occur at 40°N–60°N during December–February and August–September, and also at 40°S–60°S in April–May, with the dominance of (2, 4) during October–April and (2, 3) and (2, 5) dominance for other months. The CMAM-DAS is quite successful in reproducing the dominance of SW1 in the Antarctic summer mesosphere. The modeled SW1 shows very good overall agreement in both amplitude and phase with wind measurements from UARS High Resolution Doppler Imager and Wind Imaging Interferometer (UARS-HRDI/WINDII) and from TIMED Doppler Interferometer (TIDI). The CMAM-DAS analyses for SW3, SW4, SW6, and S0 are also in reasonable agreement with those determined from the HRDI/WINDII or TIDI wind measurements. This work provides further evidence for the tidal forcing from below.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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