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  • 1
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    Rectal insemination modifies immune responses in rabbits (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-04-27
    Description: Weekly deposition of pooled rabbit semen into the rectum in healthy male rabbits resulted in the appearance of immune complexes and antibodies to sperm and to peripheral blood lymphocyte antigens. It also led to a decreased ability to mount a humoral immune response to T lymphocyte-dependent antigens, keyhole limpet hemocyanin, and sheep red blood cells. These findings suggest that repeated rectal deposition of semen may compromise some aspects of the immune system.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Richards, J M -- Bedford, J M -- Witkin, S S -- CA 35018/CA/NCI NIH HHS/ -- HD16587/HD/NICHD NIH HHS/ -- New York, N.Y. -- Science. 1984 Apr 27;224(4647):390-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6608789" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antibodies/analysis ; *Antibody Formation ; *Antigen-Antibody Complex ; Erythrocytes/immunology ; *G(M1) Ganglioside ; Glycosphingolipids/immunology ; Hemocyanin/immunology ; Immunoglobulins/analysis ; *Insemination ; Killer Cells, Natural/immunology ; Lymphocytes/immunology ; Male ; Rabbits ; *Rectum ; Semen/*immunology ; Spermatozoa/*immunology ; T-Lymphocytes/immunology ; Time Factors
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
    Electronic Resource
    Electronic Resource
    Fertile Life of Rabbit Spermatozoa in Rat Uterus (1967)
    [s.l.] : Nature Publishing Group
    Nature 213 (1967), S. 1097-1099 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Injection of rabbit spermatozoa into the uterus of rat has demonstrated a prolongation of the fertile life of the sperm, sometimes to almost twice that in the rabbit ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/2131097a0
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Changes in the Electrophoretic Properties of Rabbit Spermatozoa During Passage Through the Epididymis (1963)
    [s.l.] : Nature Publishing Group
    Nature 200 (1963), S. 1178-1180 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] WHEN washed free of seminal plasma or taken directly from the vas deferens or cauda epididymis, motile mammalian spermatozoa exhibit a marked tendency to agglutinate by the head region if suspended in homologous heated serum, or in isotonic media containing free electrolytes1. During examination of ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/2001178a0
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  • 4
    Electronic Resource
    Electronic Resource
    Fertilization of Rabbit Ova in vitro (1962)
    [s.l.] : Nature Publishing Group
    Nature 193 (1962), S. 898-899 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] When uterine spermatozoa were collected 12 hr. after mating or insemination, using buffered, unbuffered balanced salt solutions, or a complicated synthetic culture medium such as T.C. 199, the motile life of these spermatozoa was always markedly prolonged if 5 per cent heated homologous serum had ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/193898a0
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  • 5
    Electronic Resource
    Electronic Resource
    Hamster oocyte penetrability during preovulatory maturation (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    Molecular Reproduction and Development 29 (1991), S. 72-76 
    Details
    ISSN: 1040-452X
    Keywords: Penetration ; Zona pellucida ; Granulosa cells ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: In vitro fertilization techniques were used to analyze the penetrability of preovulatory hamster oocytes. The zonas of granulosa cell-free primary (GV) oocytes were penetrated in vitro in 2-3 h as readily as those of ovulated secondary oocytes (80% vs. 88%), whether inseminated separately or as mixed oocyte groups. In fact, a significantly higher (P〈0.05) mean number of perivitelline spermatozoa was present in immature (3.6) compared with secondary (1.9) oocytes, primarily reflecting a lack of the zona block to polyspermy in the immature population. By contrast, when granulosa cells remained around GV oocytes, zona penetration was low and more were penetrated, with more spermatozoa incorporated into the vitellus as a function of increasing time of oocyte recovery after hCG. We conclude, contrary to previous reports, that the zona pellucida of the hamster GV oocyte is readily penetrable by spermatozoa in vitro. However, the resumption of meiosis brings an increase in the penetrability of the granulosa cell vestment as well as the capacity for cortical granule exocytosis and the ability to decondense and transform the fertilizing sperm nucleus. The fact that the zona pellucida of the immature oocyte has proved to be penetrable in vitro and/or in vivo in all the mammals studied in this respect is discussed with particular reference to the situation in man.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mrd.1080290111
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  • 6
    Electronic Resource
    Electronic Resource
    Sperm entry into zona-free oocytes in the hamster oviduct: Implications for the mechanisms of acrosome reaction induction (1988)
    New York, NY : Wiley-Blackwell
    Gamete Research 21 (1988), S. 85-91 
    Details
    ISSN: 0148-7280
    Keywords: zona pellucida ; oviduct ; fertilization ; acrosome reaction induction ; capacitation ; mammals ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: The possible importance of the zona pellucida for induction of the acrosome reaction (AR) and establishment of sperm/egg associations in the fallopian tube was investigated by instilling zona-free eggs into the oviductal ampulla of hamsters that had been inseminated with epididymal spermatozoa 6-7 hours previously. The eggs were recovered only 60-90 minutes later because of increasing difficulty with time of collecting zona-free eggs from the oviduct. In the zona-free group, 41 (4%) of 1,101 transferred eggs were recovered, of which 20% contained spermatozoa with decondensing nuclei (mean 4.4/egg). A similar (22%) fertilization rate (mean 3.2 spermatozoa/egg) was found among intact (control) eggs recovered after instillation into the contralateral oviduct.Mammalian spermatozoa are not incorporated even into zona-free eggs before AR occurs. These results thus demonstrate that an AR in functional hamster spermatozoa in vivo and establishment of sperm/egg associations in vivo require no interaction with the zona pellucida nor with other products of ovulation.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mrd.1120210110
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  • 7
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    Site of the mammalian sperm physiological acrosome reaction (2011)
    National Academy of Sciences
    Details
    Publication Date: 2011-03-11
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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  • 8
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    Site of the mammalian sperm physiological acrosome reaction [Commentary] (2011)
    National Academy of Sciences
    Details
    Publication Date: 2011-03-23
    Description: In mammals and the many other animals in which fertilization involves the establishment of a penetration path through the egg coat, at the apex of the sperm head lies the acrosome—a membrane-limited organelle that houses a complex of enzymes. For fertilization to occur, spermatozoa must first undergo the acrosome reaction (AR), which involves point fusions between the outer acrosomal and overlying cell membrane. This reaction releases the acrosome's soluble lysins, which facilitate the creation of a path in the egg coat during penetration (although a variety of evidence now calls into question whether egg-coat lysis is the mechanism used by...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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  • 9
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    Fertile Life of Rabbit Spermatozoa in Rat Uterus (1967)
    Springer Nature
    Details
    Publication Date: 1967-03-01
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Springer Nature
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  • 10
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    Fertilization of Rabbit Ova in vitro (1962)
    Springer Nature
    Details
    Publication Date: 1962-03-01
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Springer Nature
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