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  • 1
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1978-04-21
    Description: Fractions from used crankcase oil enriched in polyaromatic hydrocarbons induced revertant colonies in Salmonella typhimurium strain TA 98 when activated by rat or trout liver extracts. The mutagenic activity was not due to benzopyrene or benzanthracene. Fractions from various crude and refined petroleums were nonmutagenic. Among various petroleum hydrocarbons entering inland and coastal waters, used crankcase oils may represent a major mutagenic burden.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Payne, J F -- Martins, I -- Rahimtula, A -- New York, N.Y. -- Science. 1978 Apr 21;200(4339):329-30.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/635591" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biotransformation ; Fishes ; Liver/metabolism ; Mutagens/*metabolism ; Oils/metabolism ; *Petroleum ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Abstract. A non-lymphocystis type disease associated with virus particles has been documented in winter flounder, Pseudopleuronectes americanus (Walbaum), taken from a small estuary in Conception Bay, Newfoundland. The papillomatosis-type lesions found on the dorsal surface of the fish contained numerous electron-dense particles, approximately 30 nm in diameter. A number of lines of evidence, including cytochemical studies, indicated that the particles were not glycogen but virions. Sensitivity to deoxyribonuclease enzyme treatment and the presence of crystalline viral‘factories’ in the nuclei of infected cells further suggested that the particles were small DNA virions. Characteristics including nucleic acid composition, particle size, site of multiplication and the lack of an envelope indicate that this fish virus is similar to the Papovaviridae and Parvoviridae families of mammalian viruses. Lymphocystis is common in flatfish populations along the Newfoundland and Labrador coasts of the N.W. Atlantic, but this is the first record of flatfish infection with a small DNA virus.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Abstract. A non-lymphocystis type disease associated with virus particles has been documented in winter flounder, Pseudopleuronectes americanus (Walbaum), taken from a small estuary in Conception Bay, Newfoundland. The papillomatosis-type lesions found on the dorsal surface of the fish contained numerous electron-dense particles, approximately 30 nm in diameter. A number of lines of evidence, including cytochemical studies, indicated that the particles were not glycogen but virions. Sensitivity to deoxyribonuclease enzyme treatment and the presence of crystalline viral‘factories’in the nuclei of infected cells further suggested that the particles were small DNA virions. Characteristics including nucleic acid composition, particle size, site of multiplication and the lack of an envelope indicate that this fish virus is similar to the Papovaviridae and Parvoviridae families of mammalian viruses. Lymphocystis is common in flatfish populations along the Newfoundland and Labrador coasts of the N.W. Atlantic, but this is the first record of flatfish infection with a small DNA virus.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of environmental contamination and toxicology 22 (1979), S. 548-551 
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of environmental contamination and toxicology 14 (1975), S. 112-116 
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of environmental contamination and toxicology 33 (1984), S. 144-152 
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Archives of environmental contamination and toxicology 24 (1993), S. 249-257 
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Baseline concentrations of total unsaturated compounds extracted from six species of molluscs, collected from waters around Newfoundland and Labrador were determined by ultraviolet/fluorescence spectroscopy (uv/f, chrysene equivalents, IOC recommendation). Extracts of muscle tissue from scallops,Placopecten magellanicus, clams,Mya arenaria, whelks,Buccinum undatum and propeller clams,Cyrtoderia siliqua had negligible hydrocarbon concentrations compared to the corresponding visceral mass. The pattern of concentration (GC-MS) of the 16 PAH priority pollutants (EPA recommendation) was similar in the visceral mass of these species and in whole mussels (Mytilus edulis) and periwinkles (Nucella lapillus). When the 16 PAH were detected (〉5 ng/g, dry weight), fluoranthene dominated (〈200 ng/g), followed by phenanthrene-anthracene (〈50 ng/g). Extracts of the visceral mass of scallops appeared to contain a relatively larger amount of uv/f absorbing hydrocarbons; therefore, a further investigation was undertaken. A C-25 unsaturated hydrocarbon of molecular weight 346 was identified as the major component of the extraction mixture. Overall, hydrocarbon levels were very low in comparison to other geographical regions.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Archives of environmental contamination and toxicology 25 (1993), S. 497-505 
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Twenty-three specific organochlorine contaminants and polychlorinated biphenyls (PCBs), measured as three Aroclor® standards were analyzed in muscle, liver, and ovaries of cod, Gadus morhua, collected in the Northwest Atlantic. In general, contaminants were undetectable in muscle tissue, while concentrations were 10 times lower in ovaries than liver (wet weight). Comparison of results to other locations indicated a similarity between the ratio of the concentrations of p,p′-DDE, p,p′-DDD and p,p′-DDT, in liver of cod from the northern North Sea and from the Northwest Atlantic, although with lower levels in the present study. The ratio of α-HCH and γ-HCH was between that of the central and northern North Sea. Similar ratios tend to indicate similar residence times in the atmosphere, from source to sampling area. Comparison of ∑PCB and ∑DDT in the liver of cod from various geographical locations showed the following general trend in concentrations: Arctic, Northwest Atlantic, West Atlantic, Norway 〈 North Baltic, Nova Scotia, North Sea 〈 South Baltic. It was observed that if the liver concentration of one compound was low (high), there was a tendency for all compounds to be low (high). Cluster analysis of organochlorines in liver pointed to the presence of four basic clusters, which could reflect similar physical chemical properties within a group. Concentrations of organochlorines in ovaries were below levels expected to affect egg and larval viability.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Archives of environmental contamination and toxicology 21 (1991), S. 135-140 
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract There is virtually no information available on concentrations of polycyclic aromatic hydrocarbons (PAH) in seals from any of the world's oceans. The largest harp seal population in the world is found in Canadian waters of the Northwest Atlantic. Samples of muscle tissue obtained from twenty eight harp seals ranging in age from foetuses to animals 22 years old were analyzed for total PAH and lipid content. Concentrations were determined in terms of crude oil and chrysene equivalents in line with recommendations of the International Oceanographic Commission. Overall, relatively low concentrations were found, the highest values being less than 1 ppm (μg/g) in terms of chrysene equivalents and 4 ppm (μg/g) in terms of petroleum hydrocarbon equivalents. The lowest concentrations were observed in fetal tissue. There was no evidence of bioaccumulation with age, the concentrations in juvenile seals (1–5 years) being higher than concentrations in older animals (6–20 years). There was also no correlation between PAH concentration and fat content. There is a possibility that the animals having elevated levels of PAH are from the Gulf of St. Lawrence herd, indicating the importance of obtaining more information on PAH levels in marine mammals and other organisms from this and similar regionally contaminated seas.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Archives of environmental contamination and toxicology 27 (1994), S. 477-485 
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Pseudopleuronectes americanus were chronically exposed to Hibernia crude oil in sediments, for 4 months. Oil was added to sediments at five concentrations between 0.09 and 4.5 mg/g (dry weight) and was 0.10–0.90 mg/g, at the termination of the exposure. Bioaccumulation measured in terms of fluorescence or in terms of the concentration of specific aromatic targets, increased with dosage. Accumulation of hydrocarbons was observed in muscle tissue (0.22 μg/g, dry weight), when concentration of the sum of 27 polycyclic aromatic compounds (PAC) in sediments was of 0.65 μg/g (E-50), at the end of the 4-month period. Of the 27 parental and alkylated polycyclic aromatic compounds analyzed, alkylated naphthalenes predominated in muscle (90–100%) and in sediments (30–60%). Bioaccumulation factors were derived for 13 compounds detected in muscle, at the three higher exposures. Liver concentrations (fluorescence) were higher than in muscle, but did not display a noticeable dose-response. Several alkylbenzenes, a C-2 biphenyl and C-4 acenaphthene were also detected in muscle extracts. The development of dose-response relationships for polycyclic aromatic hydrocarbons (PAH) present in sediment, in relation to bioaccumulation in flatfish, is of major interest for evaluating the environmental effects of oil contamination.
    Type of Medium: Electronic Resource
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