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  • 1
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    Temporal variations of nitrogen wet deposition across Japan from 1989 to 2008 (2011)
    Wiley
    Details
    Publikationsdatum: 2011-03-26
    Beschreibung: To evaluate temporal variations in nitrogen wet deposition across Japan during 1989–2008, we analyzed results of a chemical transport model (the Models-3 Community Multiscale Air Quality) and observational data. The model successfully reproduced the general patterns of spatial and temporal variations of observed NO3− wet deposition rates. Wet deposition rates of NO3− across Japan increased during 1989–2008, with rates of increase of 2–5%/yr. Sensitivity simulations indicated that the increase of NO3− wet deposition rates was mostly (61%–94%) explained by the increased emissions of atmospheric pollutants in China. Contributions of China's emissions increased from 29%–35% during 1989–1993 to 43%–61% during 2004–2008, suggesting that transboundary pollution had a large impact on NO3− wet deposition in Japan. The contribution of observed NO3− to total nitrogen wet deposition (i.e., NO3− + NH4+) increased in southwestern Japan, and currently, NO3− and NH4+ make similar contributions to nitrogen wet deposition across Japan. Interannual variation of NO3− wet deposition was further evaluated using a meteorological index, area-weighted surface pressure anomaly (ASPA). When ASPA was negative, air masses from the Asian continent were more directly transported to Japan, and NO3− concentrations across Japan became high. Thus, anomalies of NO3− concentrations were negatively correlated with ASPA. Anomalies of NO3− wet deposition rates, however, showed a weak positive correlation with ASPA, reflecting a positive correlation between anomalies in precipitation rates and ASPA. This result strongly suggests that precipitation patterns have a large impact on the interannual variation of NO3− wet deposition across Japan.
    Print ISSN: 0148-0227
    Thema: Geologie und Paläontologie , Physik
    Publiziert von Wiley im Namen von American Geophysical Union (AGU).
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
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    Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 2002-01-19
    Beschreibung: Sympathetic nervous system (SNS) regulation of cardiac action potential duration (APD) is mediated by beta adrenergic receptor (betaAR) activation, which increases the slow outward potassium ion current (IKS). Mutations in two human I(KS) channel subunits, hKCNQ1 and hKCNE1, prolong APD and cause inherited cardiac arrhythmias known as LQTS (long QT syndrome). We show that betaAR modulation of I(KS) requires targeting of adenosine 3',5'-monophosphate (cAMP)-dependent protein kinase (PKA) and protein phosphatase 1 (PP1) to hKCNQ1 through the targeting protein yotiao. Yotiao binds to hKCNQ1 by a leucine zipper motif, which is disrupted by an LQTS mutation (hKCNQ1-G589D). Identification of the hKCNQ1 macromolecular complex provides a mechanism for SNS modulation of cardiac APD through IKS.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marx, Steven O -- Kurokawa, Junko -- Reiken, Steven -- Motoike, Howard -- D'Armiento, Jeanine -- Marks, Andrew R -- Kass, Robert S -- P01HL67849-01/HL/NHLBI NIH HHS/ -- R01-AI39794/AI/NIAID NIH HHS/ -- R01-HL44365-07/HL/NHLBI NIH HHS/ -- R01-HL56180/HL/NHLBI NIH HHS/ -- R01-HL56810-05/HL/NHLBI NIH HHS/ -- R01-HL61503/HL/NHLBI NIH HHS/ -- R01-HL68093/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 2002 Jan 18;295(5554):496-9.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Pharmacology, Center for Molecular Cardiology, Department of Medicine, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11799244" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): 8-Bromo Cyclic Adenosine Monophosphate/pharmacology ; A Kinase Anchor Proteins ; Action Potentials ; *Adaptor Proteins, Signal Transducing ; Amino Acid Substitution ; Animals ; CHO Cells ; Carrier Proteins/*metabolism ; Cricetinae ; Cyclic AMP/metabolism ; Cyclic AMP-Dependent Protein Kinases/*metabolism ; Cytoskeletal Proteins/*metabolism ; Humans ; KCNQ Potassium Channels ; KCNQ1 Potassium Channel ; Leucine Zippers ; Macromolecular Substances ; Mice ; Mice, Transgenic ; Mutation ; Myocardium/cytology/*metabolism ; Phosphoprotein Phosphatases/*metabolism ; Phosphorylation ; Potassium/metabolism ; Potassium Channels/chemistry/genetics/*metabolism ; *Potassium Channels, Voltage-Gated ; Protein Phosphatase 1 ; Receptors, Adrenergic, beta/*metabolism ; Recombinant Fusion Proteins/chemistry/metabolism ; Signal Transduction
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
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    Clostridium thermocellum cellulase CelT, a family 9 endoglucanase without an Ig-like domain or family 3c carbohydrate-binding module (2002)
    Springer
    Details
    Publikationsdatum: 2002-01-01
    Print ISSN: 0175-7598
    Digitale ISSN: 1432-0614
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Publiziert von Springer
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
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    Rising critical emission of air pollutants from renewable biomass based cogeneration from the sugar industry in India (2015)
    Institute of Physics (IOP)
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    Publikationsdatum: 2015-09-02
    Beschreibung: In the recent past, the emerging India economy is highly dependent on conventional as well as renewable energy to deal with energy security. Keeping the potential of biomass and its plentiful availability, the Indian government has been encouraging various industrial sectors to generate their own energy from it. The Indian sugar industry has adopted and made impressive growth in bagasse (a renewable biomass, i.e. left after sugercane is crushed) based cogeneration power to fulfil their energy need, as well as to export a big chunk of energy to grid power. Like fossil fuel, bagasse combustion also generates various critical pollutants. This article provides the first ever estimation, current status and overview of magnitude of air pollutant emissions from rapidly growing bagasse based cogeneration technology in Indian sugar mills. The estimated emission from the world’s second largest sugar industry in India for particulate matter, NO X, SO 2 , CO and CO 2
    Print ISSN: 1748-9318
    Digitale ISSN: 1748-9326
    Thema: Biologie , Energietechnik
    Publiziert von Institute of Physics (IOP)
    Standort Signatur Erwartet Verfügbarkeit
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