ISSN:
1432-041X
Keywords:
Key words Wnt
;
Zebrafish
;
Viscera
;
Brain
;
Neural tube
;
Tailbud
;
Presomitic mesoderm
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract Proteins encoded by the Wnt family of genes act as signals and have been shown to play important roles in a wide variety of developmental processes. Here we describe the cloning of three Wnt family members from the zebrafish, Danio rerio, which encode proteins with homology to murine Wnt-2, -4 and -5A/B. The expression patterns of the latter two zebrafish genes, designated ZfWnt4 and ZfWnt5 show considerable similarity with their homologues in other vertebrates; ZfWnt2, however, is expressed in the developing viscera in a pattern distinct from its closest murine homologue. In the light of the similarities and differences in the patterns of expression of these genes relative to their homologues in other vertebrates, we speculate on their possible functions.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s004270050025
Permalink