ISSN:
0021-8383
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
3-Mercapto-5,6-diphenyl-1,2,4-triazine 1a reacts with GRIGNARD reagents to give 2b-g. 6-Phenyl-3-mercapto-5-oxo-4,5-dihydro-1,2,4-triazine 4a reacts with phenylmagnesium bromide to form 5, 1a and 2g. 6-Phenyl-3-methylmercapto-5-oxo-4,5-dihydro-1,2,4-triazine 4b reacts with phenylmagnesium bromide to give 1b. Compound 1b reacts with methyl- and /or ethylmagnesium iodide to give 2h and 2c respectively. Compounds 1b, 4b and 2h react with hydrogen peroxide to give 6, 7 and 3a respectively. The reactivity of the C=N in position 4,5 in 1a has been further illustrated by its ready reduction with p-thiocresol to give 2a. The action of ethereal diazomethane on 1a gives 1b.
Additional Material:
1 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19723140526
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