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  • 1
    Publication Date: 2016-09-07
    Description: In this paper, the asymptotic stability of uncertain discrete switched systems with interval time-varying delay and linear fractional perturbations is achieved via switching signal design. Some linear matrix inequality (LMI) stability criteria are provided to design the switching signal by the proposed non-uniform delay-partitioning approach. Finally, some numerical examples are illustrated to show the main developed results.
    Print ISSN: 0265-0754
    Electronic ISSN: 1471-6887
    Topics: Mathematics
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  • 2
    Publication Date: 2011-11-09
    Description: TNF receptor-associated factor 2 (TRAF2) is a key intracellular signaling mediator that acts downstream of not only TNFα but also various members of the TNFα superfamily. Here, we report that, despite their lack of TNFα signaling, TRAF2−/−TNFα−/− mice develop an inflammatory disorder characterized by autoantibody accumulation and organ infiltration by T cells with the phenotypes of activated, effector, and memory cells. RAG1−/− mice reconstituted with TRAF2−/−TNFα−/− bone marrow cells showed increased numbers of hyperactive T cells and rapidly developed progressive and eventually lethal inflammation. No inflammation was observed in RAG1−/− mice reconstituted with TRAF2−/−TNFα−/−T-cell receptor β−/− or TRAF2−/−TNFα−/−NFκB-induced kinase+/− bone marrow cells. The pathogenic TRAF2−/−TNFα−/− T cells showed constitutive NFκB2p52 activation and produced elevated levels of T-helper 1 and T-helper 17 cytokines. Our results suggest that a regulatory circuit consisting of TRAF2–NFκB-induced kinase–NFκB2p52 is essential for the proper control of effector T-cell polarization and that loss of T-cell TRAF2 function induces constitutive NFκB2p52 activity that drives fatal autoimmune inflammation independently of TNFα signaling. The involvement of this regulatory circuit in controlling autoimmune responses highlights the delicate balance required to avoid paradoxical adverse events when implementing new targeted anti-inflammatory therapies.
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 3
    Publication Date: 1997-01-17
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ramamoorthy, K -- Wang, F -- Chen, I C -- Safe, S -- Norris, J D -- McDonnell, D P -- Gaido, K W -- Bocchinfuso, W P -- Korach, K S -- New York, N.Y. -- Science. 1997 Jan 17;275(5298):405-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9005556" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Dieldrin/metabolism/*pharmacology ; Drug Interactions ; Drug Synergism ; Estrogens, Non-Steroidal/metabolism/*pharmacology ; Female ; Humans ; Insecticides/metabolism/*pharmacology ; Mice ; Receptors, Estrogen/metabolism ; Toxaphene/metabolism/*pharmacology ; Tumor Cells, Cultured
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
    Publication Date: 2011-08-20
    Description: The distributions of many terrestrial organisms are currently shifting in latitude or elevation in response to changing climate. Using a meta-analysis, we estimated that the distributions of species have recently shifted to higher elevations at a median rate of 11.0 meters per decade, and to higher latitudes at a median rate of 16.9 kilometers per decade. These rates are approximately two and three times faster than previously reported. The distances moved by species are greatest in studies showing the highest levels of warming, with average latitudinal shifts being generally sufficient to track temperature changes. However, individual species vary greatly in their rates of change, suggesting that the range shift of each species depends on multiple internal species traits and external drivers of change. Rapid average shifts derive from a wide diversity of responses by individual species.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chen, I-Ching -- Hill, Jane K -- Ohlemuller, Ralf -- Roy, David B -- Thomas, Chris D -- New York, N.Y. -- Science. 2011 Aug 19;333(6045):1024-6. doi: 10.1126/science.1206432.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biology, University of York, Wentworth Way, York YO10 5DD, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21852500" target="_blank"〉PubMed〈/a〉
    Keywords: *Altitude ; Animals ; *Behavior, Animal ; *Climate Change ; *Ecosystem ; *Environment ; Geography ; Population Dynamics ; Species Specificity ; Time Factors
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
    Publication Date: 2016-03-26
    Description: The climatic variability hypothesis posits that the magnitude of climatic variability increases with latitude, elevation, or both, and that greater variability selects for organisms with broader temperature tolerances, enabling them to be geographically widespread. We tested this classical hypothesis for the elevational range sizes of more than 16,500 terrestrial vertebrates on 180 montane gradients. In support of the hypothesis, mean elevational range size was positively correlated with the scope of seasonal temperature variation, whereas elevational range size was negatively correlated with daily temperature variation among gradients. In accordance with a previous life history model and our extended versions of it, our findings indicate that physiological specialization may be favored under shorter-term climatic variability.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chan, Wei-Ping -- Chen, I-Ching -- Colwell, Robert K -- Liu, Wei-Chung -- Huang, Cho-Ying -- Shen, Sheng-Feng -- New York, N.Y. -- Science. 2016 Mar 25;351(6280):1437-9. doi: 10.1126/science.aab4119.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Biodiversity Research Center, Academia Sinica, Taipei 11529, Taiwan. ; Biodiversity Research Center, Academia Sinica, Taipei 11529, Taiwan. Department of Life Sciences, National Cheng Kung University, Tainan 70101, Taiwan. ; Department of Ecology and Evolutionary Biology, University of Connecticut, Storrs, CT 06269, USA. University of Colorado Museum of Natural History, Boulder, CO 80309, USA. Departmento de Ecologia, Universidade Federal de Goias, CP 131, 74.001-970 Goiania, Goias, Brazil. ; Institute of Statistical Science, Academia Sinica, Taipei 11529, Taiwan. ; Department of Geography, National Taiwan University, Taipei 10617, Taiwan. ; Biodiversity Research Center, Academia Sinica, Taipei 11529, Taiwan. shensf@sinica.edu.tw.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/27013729" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Climate ; *Global Warming ; *Seasons ; *Temperature ; Vertebrates/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 70 (1991), S. 1844-1846 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The susceptibility to hole trapping of the gate oxide of a metal-oxide-silicon (MOS) device is not necessarily proportional to the efficiency of interface trap generation at the Si-SiO2 interface, which is widely believed due to the recombination of electrons and trapped holes in the oxide close to the interface. In this study, an oxide given a high-temperature (1000 °C) anneal, which increases the hole trapping efficiency of the oxide, is shown to have much less generated interface traps compared to a normal oxide (without high-temperature annealing) upon exposing to ionizing radiation with subsequent electron injection, or high-field injection alone. Under high-field tunneling injection, the electron fluence required to create a certain density of interface trap is an order of magnitude higher for the annealed oxide compared to the normal oxide. These results could provide a possible direction for improving the reliability of the gate oxide of a MOS field-effect transistor.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 61 (1987), S. 4544-4548 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: It is shown that after holes are injected and trapped in silicon dioxide (SiO2), subsequent electron injection will generate neutral electron traps. The density of electron traps generated is about 30% of the density of trapped holes. It is proposed that electron traps are created by the energy released through the recombination of electrons and holes, and that this is the mechanism of electron-trap generation during high-field oxide stressing. Similar oxide field and thickness dependencies of the rate of electron-trap generation and hole generation further support this model. This model can reconcile the main evidence for the electron-trapping oxide breakdown model with the hole-trapping breakdown model. It is consistent with the higher trap generation rate in irradiated SiO2. An analytical trapping model is derived and the electron capture cross sections of trapped holes and the generated neutral traps are found to be 10−14 cm2 and 5×10−16 cm2, respectively.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: : The quality of phytoestrogenic licorice was studied by using both chemical and biological fingerprints. A recombinant yeast strain that consists of an estrogen responsive element linked with a reporter gene (ADE2) and a transformed human estrogen receptor–containing plasmid was used for screening and evaluation of estrogenic activity in licorice. Several estrogen-like components in licorice were screened, and licoisoflavone B and formononetin were identified. Licorice extracted with 70% ethanol showed 5 different patterns of chemical fingerprints (LR-A, LR-E, LR-F, LR-H, LR-K), as identified by chromatographic analysis. Among these, LR-E exhibited the strongest estrogenic activity, whereas LR-A, LR-F, and LR-H were in the middle, and LR-K had the weakest activity.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 60 (1995), S. 0 
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Sturgeon species have attracted interest for aquaculture due to high value of the flesh, caviar and wild stock depletion. Lipid was extracted from sturgeon muscle using the Bligh and Dyer procedure. Fatty acids from total lipid were methylated using boron-trifluoride in methanol. Fatty acid methyl esters were analyzed by gas chromatography as weight %. The fatty acid profiles of lipids were different between cultured and wild sturgeon. Wild sturgeon had higher levels of 16:0, 16:1ω7, 18:1ω9, 22: 4ω6 and 22:5ω6. Cultured fish had higher levels of 18:2ω6, C20 and C22 monoenes, 20:5ω3 and 22:6ω3. Stepwise discriminant analysis (SDA) was used to develop a mathematical model to distinguish the two populations; the levels of 16:2ω6, 22:5ω6 and phytanic acid accurately identified the two fish populations.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 61 (1996), S. 0 
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and isoelectric focusing (IEF) analyses of caviar were used to identify species of American, European and Asian sturgeon. Caviar samples of American and Gulf of Mexico sturgeon showed distinctive protein banding patterns on SDS-PAGE. IEF gels containing 20% pH 3-10 and 80% pH 4-6.5 ampholyte enabled differentiation of sturgeon species. IEF was more reliable than SDS-PAGE for identification of sturgeon species.
    Type of Medium: Electronic Resource
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