ISSN:
0268-2605
Keywords:
Organotin compounds
;
speciation
;
high-performance liquid chromatography
;
inductively coupled plasma-mass spectrometry
;
Chemistry
;
Industrial Chemistry and Chemical Engineering
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
An evaluation of reversed-phase high-performance liquid chromatography (HPLC) employing mobile phases compatible with direct coupling to inductively coupled plasma-mass spectrometry (ICP-MS) is described for the selective and sensitive detection of organotin species. The findings of this study are compared with established methods, employing ion-exchange chromatography.In order to achieve optimum performance, both the HPLC and ICP-MS were optimized for speciation work. The results from studies using various mobile phases for the separation of a range of tin compounds (inorganic tin, tributyltin, dibutyltin and monobutyltin) are discussed both in terms of resolution and compatibility with ICP-MS instrumentation. Tropolone, a commonly used complexing agent for organotin species, is also discussed with reference to the chromatographic separation of tin species.Finally, the role of isotope dilution analysis in conjunction with HPLC-ICP-MS for organotin speciation is described with respect to the European Community Standards, Measurements and Testing (BCR) certified material programme.
Additional Material:
5 Ill.
Type of Medium:
Electronic Resource
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