Publication Date:
2018-01-30
Description:
Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols, Published online: 29 January 2018; doi:10.1038/s41467-017-02698-4 Chiral vicinal amino alcohols are found in many bioactive compounds and may serve as chiral ligands. Here, the authors report a photocatalytic enantioselective cross-coupling of nitrones with aromatic aldehydes with a chiral ligand-coordinated rare earth ion synergistically producing enantiopure vicinal amino alcohols.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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