Publication Date:
2012-11-16
Description:
Abstract 4633 Case presentation A 1 day old male presented to local hospital in collapsed state following normal vaginal delivery at 41 weeks gestation. The baby had sudden onset of limpness at home. On arrival at hospital he was making no spontaneous movement had slowly reactive pupils, oxygen saturation was 76% in air. He was intubated and blood was noted on his vocal cords. His haemoglobin was 2.3g/dl and coagulation grossly abnormal with APTT of 〉100seconds. There was no family history of bleeding diathesis. The baby was transferred to neonatal intensive care unit at this hospital. Management On arrival at this hospital the baby was ventilated, had received both FFP and blood transfusion and an additional dose of Vitamin K whilst clotting factor assays were awaited. Abdominal distention was noted and an ultra sound of the abdomen revealed a large collection of blood in the abdominal cavity. Severe vWD (FVIII 8iu/dl and VWF Rapid 5iu/dl post FFP) was diagnosed. Treatment with Wilate 60iu/kg/dose was initiated and continued for 7 days during which time there was no further bleeding. Outcomes The baby was ventilated for 72 hours, a central line was inserted for venous access and administration of Wilate. Subsequent factor assays (with out FFP) reveal FVIII
Print ISSN:
0006-4971
Electronic ISSN:
1528-0020
Topics:
Biology
,
Medicine
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