ISSN:
1573-3297
Keywords:
alcohol
;
heart rate
;
blood pressure
;
race
;
genetics
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Psychology
Notes:
Abstract Cardiovascular responses (changes in heart rate, systolic and diastolic blood pressure) of 103 normal young adult males (46 European, 30 Japanese, 27 Chinese) to a test drink of alcohol were analyzed. The two Oriental groups did not differ in their mean responses (measured as postdrink value minus baseline value). When these two groups were pooled as “Orientals,” they differed very significantly from Europeans in their responses. Each of the three groups showed marked between-individual variability in alcohol response for each cardiovascular parameter, in the absence of obvious environmental differences. Repeated-measures ANOVA on these and other data, plus a direct genetic study in mice of the heritability of alcohol-induced change in heart rate, indicates that the broad-sense heritability of such changes in humans is in the region 0.3 to 0.5.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01066285
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