Publication Date:
2019-10-23
Description:
Various aryl-substituted purine derivatives were synthesized through the direct arylation of halopurines with aromatic compounds, facilitated by the combination of triflic acid and fluoroalcohol. This metal-free method is complementary to conventional coupling reactions using metal catalysts and reagents for the syntheses of aryl-substituted purine analogues.
Electronic ISSN:
1420-3049
Topics:
Chemistry and Pharmacology
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