ISSN:
1432-1203
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Analysis of α-thalassemia syndromes in several German families revealed DNA deletion as well as nondeletion forms as the molecular basis for the defects. Thus, the α-thalassemia haplotype was identified as the (−α)3.7 rightward deletion form, and the region of the putative recombination process generating such a deletion was further characterized. In addition three different α° haplotypes, (--)MED, (--)〉26, and (αα)T, could be detected using α-and ζ-globin gene-specific probes.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00283368
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