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  • 1
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 296 (1982), S. 751-754 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] All experiments were performed on isolated fragments of rat thyroid superfused with modified Krebs-Henseleit solution, gassed with 95% O2, 5% CO2 and maintained at 37 C (ref. 10). Mixed fragments (5-10 mg) of the thyroid glands from 16 rats were placed in 8 small Perspex flow chambers (vol 0.6 ml, ...
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 34 (1988), S. 47-50 
    ISSN: 1432-1041
    Keywords: isosorbide-5-mononitrate ; food intake ; slow-release formulation ; absorption rate ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The influence of food on the absorption characteristics of slow release isosorbide-5-mononitrate tablets was investigated in 10 normal healthy volunteers. There were no differences in the peak concentration achieved or the area under the curve, but the peak concentration occurred later when the drug was administered after food. The apparent elimination half-life ranged from 4.7 to 10.1 h. Bioavailability of slow-release isosorbide-5-mononitrate is therefore unaffected by food, but there is a slower rate of absorption.
    Type of Medium: Electronic Resource
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  • 3
    Publication Date: 1988-01-01
    Print ISSN: 0031-6970
    Electronic ISSN: 1432-1041
    Topics: Chemistry and Pharmacology , Medicine
    Published by Springer
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  • 4
    Publication Date: 1982-04-01
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Springer Nature
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  • 5
    Publication Date: 2019-07-17
    Description: One of the goals of NASA''s HEDS enterprise is to establish a long-term human presence on Mars at a fraction of the cost of employing today''s technology. The most direct method of reducing mission cost is to reduce the launch mass of the spacecraft. If the propellants for the return phase of the mission are produced on Mars, the total spacecraft mass could be reduced significantly. An interim goal is a Mars Sample Return (MSR) mission, which is proposed to demonstrate the feasibility of in-situ propellant production (ISPP). Five candidate ISPP systems for producing two fuels and oxygen from the Martian atmosphere are considered in this design trade-off study:(1) Zirconia cell with methanol synthesis, (2) Reverse water gas shift (RWGS) with water electrolysis and methanol synthesis, (3) Sabatier process for methane production with water electrolysis, (4) Sabatier process with water electrolysis and partial methane pyrolysis, and (5) Sabatier/RWGS combination with water electrolysis. These systems have been the subject of numerous previous analytical studies and laboratory demonstrations. In this investigation, the systems are objectively compared on the basis of thermochemical performance models using a commonly used chemical plant analysis software package. The realistic effects of incomplete chemical conversion and gas phase separator performance are included in these models. This study focuses on the chemical processing and product separation subsystems. The CO2 compression upstream of the chemical plane and the liquefaction/storage components are not included here.
    Keywords: Engineering (General)
    Type: Abstracts In Situ Resource Utilization (ISRU 3) Technical Interchange Meeting: Abstracts; 11-12; LPI-Contrib-963
    Format: text
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  • 6
    Publication Date: 2019-07-17
    Description: One of the goals of NASA's HEDS enterprise is to establish a long-term human presence on Mars at a fraction of the cost of employing today's technology. The most direct method of reducing mission cost is to reduce the launch mass of the spacecraft. If the propellants for the return phase of the mission are produced on Mars, the total spacecraft mass could be reduced significantly. An interim goal is a Mars Sample Return (MSR) mission, which is proposed to demonstrate the feasibility of in-situ propellant production (ISPP). Five candidate ISPP systems for producing two fuels and oxygen from the Martian atmosphere are considered in this design trade-off study: 1) Zirconia cell with methanol synthesis, 2) Reverse water gas shift with water electrolysis and methanol synthesis, 3) Sabatier process for methane product ion with water electrolysis, 4) Sabatier process with water electrolysis and partial methane pyrolysis, and 5) Sabatier/RWGS combination with water electrolysis.
    Keywords: Propellants and Fuels
    Type: In Situ Resource Utilization (ISRU 3) Technical Interchange Meeting: Abstracts; 11-12; LPI-Contrib-963
    Format: text
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  • 7
    Publication Date: 2019-07-12
    Description: The theory of linearized, low-gravity sloshing in axisymmetric tanks is developed in an integral minimization form that permits numerical solutions to be computed easily and that can be modified readily when better knowledge about the important surface physics phenomena becomes available from space experimentation. The slosh force and equivalent mechanical model are also derived, including the correction of errors in previous analyses. Several numerical examples are presented for spherical and cylindrical tanks. The contact angle used in the examples is 5 deg and a 'free' contact line is assumed. The results show that the nondimensional slosh frequency and slosh mass for a spherical tank are smaller for low gravity conditions than for normal gravity conditions, whereas they are larger for cylindrical tank.
    Keywords: FLUID MECHANICS AND HEAT TRANSFER
    Type: Microgravity Science and Technology (ISSN 0938-0108); 4; 228-234
    Format: text
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  • 8
    Publication Date: 2019-07-10
    Description: The Liquid Motion Experiment (LME), which flew on STS 84 in May 1997, was an investigation of liquid motions in spinning, nutating tanks. LME was designed to quantify the effects of such liquid motions on the stability of spinning spacecraft, which are known to be adversely affected by the energy dissipated by the liquid motions. The LME hardware was essentially a spin table which could be forced to nutate at specified frequencies at a constant cone angle, independently of the spin rate. Cylindrical and spherical test tanks, partially filled with liquids of different viscosities, were located at the periphery of the spin table to simulate a spacecraft with off-axis propellant tanks; one set of tanks contained generic propellant management devices (PMDs). The primary quantitative data from the flight tests were the liquid-induced torques exerted on the tanks about radial and tangential axes through the center of the tank. Visual recordings of the liquid oscillations also provided qualitative information. The flight program incorporated two types of tests: sine sweep tests, in which the spin rate was held constant and the nutation frequency varied over a wide range; and sine dwell test, in which both the spin rate and the nutation frequency were held constant. The sine sweep tests were meant to investigate all the prominent liquid resonant oscillations and the damping of the resonances, and the sine dwell tests were meant to quantify the viscous energy dissipation rate of the liquid oscillations for steady state conditions. The LME flight data were compared to analytical results obtained from two companion IR&D programs at Southwest Research Institute. The comparisons indicated that the models predicted the observed liquid resonances, damping, and energy dissipation rates for many test conditions but not for all. It was concluded that improved models and CFD simulations are needed to resolve the differences. This work is ongoing under a current IR&D program.
    Keywords: Spacecraft Propulsion and Power
    Type: NASA/CR-1998-208667 , NAS 1.26:208667 , E-11385 , Rept-6322-FNL-01
    Format: application/pdf
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