ISSN:
1573-9171
Keywords:
methyltrifluoropyruvate
;
2-(3,4-dimethoxyphenyl)ethylamine
;
tryptamine
;
(D,L)-tryptophan
;
Pictet-Spengler reaction
;
1,2,3,4-tetrahydroisoquinolines
;
1,2,3,4-tetrahydro-β-carbolines
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract Condensation of methyl trifluoropyruvate with 2-(3,4-dimethoxyphenyl)ethylamine, tryptamine, and (D, L)-tryptophan yielded 1-methoxycarbonyl-1-trifluoromethyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline, 1-methoxycarbonyl-1-trifluoromethyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole, and Z-1-methoxycarbonyl-1-trifluoromethyl-3-carboxy-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole, respectively. The Z configuration of the latter was determined by x-ray structural analysis.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00864340
Permalink