ISSN:
1420-9071
Keywords:
Mice
;
pregnant
;
aminoglutethimide phosphate
;
mice
;
liver
;
fetal
;
erythroid colony-forming cells
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Pretreatment of pregnant mice with aminoglutethimide phosphate, an inhibitor of glucocorticoid synthesis, increases the content of fetal liver erythroid colony-forming cells (CFU-E), as assessed by the formation of erythroid colonies in vitro by fetal liver cells in plasma clots containing exogenous erythropoietin. In addition, the inability of aminoglutethimide to influence erythroid colony formation in vitro suggests that endogenous glucocorticoids exert a suppressive effect on the number of functional CFU-E in the fetal liver.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01966168
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