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  • 1
    ISSN: 1572-9702
    Keywords: Methomyl ; bendiocarb ; toxicity ; action ; Acaridae.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Methomyl was 15 and 31.3 times more toxic than bendiocarb to bulb mites at the LC50 and LC90 values respectively. However, methomyl (pI50 3.0) was at least 126 times less active than bendiocarb (pI50 5.1) as an inhibitor of bulb mite cholinesterase in vitro. The disparity between the high toxicity of methomyl and its extremely low activity as an inhibitor of mite cholinesterase in vitro indicated that another mechanism was likely involved in its toxic action. Pharmacokinetic studies of methomyl and bendiocarb showed that penetration and metabolism were rapid and that there were no substantial differences in the internal levels of the respective parent carbamates during the 24 h test period. However, volatile radioactive material(s), some of which was carbon dioxide, was produced in appreciably greater amounts from methomyl than from bendiocarb. We speculate that the production of volatiles, such as carbon dioxide, acetonitrile and/or methylamine, may contribute to the toxicity of methomyl to bulb mites. © Rapid Science Ltd. 1998
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Experimental and applied acarology 22 (1998), S. 343-351 
    ISSN: 1572-9702
    Keywords: Acaricides ; toxicity ; Acaridae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Using a continuous exposure technique, the toxicity of 35 compounds to the bulb mite, Rhizoglyphus echinopus (Fumouze and Robin) was examined after 48 h. Sixteen acaricides yielded an LC50 of 〈1.0 mg cm2. The highest toxicity was exhibited by cyclodiene GABA antagonists (dieldrin, endrin and aldrin), some organophosphate (chlorpyrifos, diazinon and azinphosethyl) and carbamate (carbofuran) anticholinesterases and a thiazolidine flubenzimine. Oxythioquinox, fenazaflor, fenazaquin and amitraz were less toxic than the cyclodienes, organophosphates and carbamates. The sodium channel agonists (DDT and pyrethroids) and several specific acaricides with other modes of action were inactive (LC50 〉11.0 mg cm-2).
    Type of Medium: Electronic Resource
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