Publication Date:
1983-06-10
Description:
Exposure of C57BL/6J mice to ionizing radiation caused stereotypical locomotor hyperactivity similar to that produced by morphine. Naloxone administration prevented this radiation-induced behavioral activation. These results support the hypothesis that endorphins are involved in some aspects of radiogenic behavioral change.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mickley, G A -- Stevens, K E -- White, G A -- Gibbs, G L -- New York, N.Y. -- Science. 1983 Jun 10;220(4602):1185-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6857244" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Behavior, Animal/drug effects/physiology/*radiation effects
;
Dose-Response Relationship, Radiation
;
Endorphins/*physiology
;
Male
;
Mice
;
Mice, Inbred C57BL
;
Motor Activity/radiation effects
;
Naloxone/pharmacology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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