Publication Date:
2019-04-17
Description:
Winery by-products, including pomace, stem, vine leaves and shoots, arise in high amounts during the wine-making process. Due to high contents of secondary plant metabolites, such as polyphenols, their usage in the food, cosmetics and pharmaceutical industry is possible. In this study, we investigated effects of an extract prepared from vine shoots (Vitis vinifera L. cv. Riesling) on riboflavin-induced DNA damage in human hepatocellular carcinoma cells HepG2 by comet assay. Significant decreases of DNA damages were detected after 2 h and 24 h extract incubation at concentration ranges of 1 to 30 µg/mL (2 h) and 1 to 10 µg/mL (24 h), respectively. These effects may be attributable to polyphenolic compounds, which has to be further investigated.
Electronic ISSN:
2504-3900
Topics:
Technology
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