Publication Date:
2018-10-03
Description:
Molecular architecture and regulation of BCL10-MALT1 filaments Molecular architecture and regulation of BCL10-MALT1 filaments, Published online: 02 October 2018; doi:10.1038/s41467-018-06573-8 The BCL10-MALT1 complex is a central signaling hub in lymphocytes and linked to various human immune pathologies. Here the authors present the cryo-EM structure of the BCL10-MALT1 filament core and verify the identified BCL10/MALT1 interface with mutagenesis studies.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
Permalink