ISSN:
1432-1203
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary We determined by restriction mapping the frequency of the −α3.7 determinant in a random sample of 48 adults in Northern Sardinia. We found a frequency of 0.18±0.04 and demonstrated that only type I crossover as determined by Apa I digestion (Higgs et al. 1984) is present. Moreover, we showed that this haplotype is not associated with an Rsa I polymorphism 5′ to the α2-globin gene. These data support the hypothesis of a unique origin of this deletion in Sardinia.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00283371
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