Publication Date:
1985-08-09
Description:
A lymphotropic virus HTLV-III/LAV was recently identified as the etiologic agent of the acquired immune deficiency syndrome (AIDS). In a study of concomitant hepatitis B infections in patients with AIDS or the AIDS-related complex, DNA sequences of hepatitis B virus (HBV) were found in fresh and cultured lymphocytes from patients with AIDS even in the absence of conventional HBV serological markers. Furthermore, the restriction DNA pattern was consistent with the integration of the viral DNA. These results should prompt additional studies to reevaluate a possible role of HBV as a cofactor in AIDS in addition to the HTLV-III/LAV causal agent.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Laure, F -- Zagury, D -- Saimot, A G -- Gallo, R C -- Hahn, B H -- Brechot, C -- New York, N.Y. -- Science. 1985 Aug 9;229(4713):561-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2410981" target="_blank"〉PubMed〈/a〉
Keywords:
Acquired Immunodeficiency Syndrome/*microbiology
;
Antibodies, Viral/analysis
;
Antigens, Viral/analysis
;
Base Sequence
;
DNA, Viral/*analysis
;
Deltaretrovirus/immunology
;
Hepatitis B/complications
;
Hepatitis B Antibodies/analysis
;
Hepatitis B Surface Antigens/analysis
;
Hepatitis B virus/*genetics/immunology
;
Humans
;
Lymphocytes/*analysis
;
RNA-Directed DNA Polymerase/analysis
;
Serologic Tests
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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