Publication Date:
2016-12-01
Description:
Fatty acid metabolic reprogramming via mTOR-mediated inductions of PPARγ directs early activation of T cells Nature Communications, Published online: 30 November 2016; doi:10.1038/ncomms13683 PPARγ promotes free fatty acid uptake and also has a role in T cell regulation. Here the authors show that mTORC1-PPARγ signalling is needed for fatty acid uptake by activated CD4 + T cells and for clonal expansion of these cells.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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