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  • 1
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    Ballenas, delfines y marsopas del Pacifico nororiental y de las aguas árticas adyacentes (2021)
    Inter-American Tropical Tuna Commission | La Jolla, CA
    In:  http://aquaticcommons.org/id/eprint/6468 | 8 | 2011-09-29 13:33:57 | 6468 | Inter-American Tropical Tuna Commission
    Details
    Publication Date: 2021-07-14
    Description: Esta guía de campo se ha diseñado para que los observadores puedan identificar los cetáceos (ballenas, delfines y marsopas) que vean en las aguas del Pacifico nororiental, incluyendo el Golfo de California, Hawaii y el Ártico occidental de Norteamérica. Los animales descritos no se agrupan por sus relaciones científicas sino por las similitudes de su apariencia en el campo. Las fotografías de los animales en su ambiente natural son la principal ayuda para su identificación. Los anexos describen como y a quienes se debe reportar la información sobre cetáceos vivos y muertos y proveen detalles para ayudar en la identificación de los cetáceos varados.
    Keywords: Fisheries
    Repository Name: AquaDocs
    Type: monograph
    Format: application/pdf
    Format: application/pdf
    Format: 256
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  • 2
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    Whales, dolphins, and porpoises of the eastern North Pacific and adjacent Arctic waters: a guide to their identification (2021)
    U.S. Department of Commerce, National Oceanic and Atmospheric Administration, National Marine Fisheries Service | Seattle, WA
    In:  Sonja.Kromann@noaa.gov | http://aquaticcommons.org/id/eprint/1402 | 155 | 2011-09-29 20:39:51 | 1402 | United States National Marine Fisheries Service
    Details
    Publication Date: 2021-07-08
    Description: This is an identification guide for cetaceans (whales, dolphins, and porpoises), that was designed to assist laymen in identifying cetaceans encountered in eastern North Pacific and Arctic waters. It was intended for use by ongoing cetacean observer programs. This is a revision of an earlier guide with the same title published in 1972 by the Naval Undersa Center and the National Marine Fisheries Service. It includes sections on identifying cetaceans at sea as well as stranded animals on shore. Species accounts are divided by body size and presence or lack of a dorsal fin. Appendices include illustrations of tags on whales, dolphins, and porpoises, by Larry Hobbs; how to record data from observed cetaceans at sea and for stranded cetaceans; and a list of cetacean names in Japanese and Russian. (Document contains 245 pages - file takes considerable time to open)
    Description: National Marine Mammal Laboratory, Northwest and Alaska Fisheries Science Center, NMFS, NOAA
    Description: Scanned by the Alaska Fisheries Science Center, August 2008.
    Keywords: Ecology ; Conservation ; Management ; Fisheries ; Biology ; Environment ; whale ; dolphin ; porpoise ; cetacean ; marine mammal ; species identification ; North Pacific Ocean ; Arctic Ocean ; National Oceanic and Atmospheric Administration ; National Marine Fisheries Service
    Repository Name: AquaDocs
    Type: monograph
    Format: application/pdf
    Format: application/pdf
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  • 3
    Electronic Resource
    Electronic Resource
    SUGAR ALCOHOLS. X: The Effect of Certain Sugar Alcohols and Their Anhydrides on the Dissociation of Boric Acid (1938)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 42 (1938), S. 507-513 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/j100899a006
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    The Synthesis of Organic Compounds Labelled with Isotopic Carbon1 (1947)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 69 (1947), S. 1110-1112 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja01197a037
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  • 5
    Electronic Resource
    Electronic Resource
    Memories (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Marine mammal science 8 (1992), S. 0 
    Details
    ISSN: 1748-7692
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1748-7692.1992.tb00419.x
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  • 6
    Electronic Resource
    Electronic Resource
    PHARMACOGENOMICS: The Inherited Basis for Interindividual Differences in Drug Response (2001)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Genomics and Human Genetics 2 (2001), S. 9-39 
    Details
    ISSN: 1527-8204
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology
    Notes: Abstract It is well recognized that most medications exhibit wide interpatient variability in their efficacy and toxicity. For many medications, these interindividual differences are due in part to polymorphisms in genes encoding drug metabolizing enzymes, drug transporters, and/or drug targets (e.g., receptors, enzymes). Pharmacogenomics is a burgeoning field aimed at elucidating the genetic basis for differences in drug efficacy and toxicity, and it uses genome-wide approaches to identify the network of genes that govern an individual's response to drug therapy. For some genetic polymorphisms (e.g., thiopurine S-methyltransferase), monogenic traits have a marked effect on pharmacokinetics (e.g., drug metabolism), such that individuals who inherit an enzyme deficiency must be treated with markedly different doses of the affected medications (e.g., 5%-10% of the standard thiopurine dose). Likewise, polymorphisms in drug targets (e.g., beta adrenergic receptor) can alter the sensitivity of patients to treatment (e.g., beta-agonists), changing the pharmacodynamics of drug response. Recognizing that most drug effects are determined by the interplay of several gene products that govern the pharmacokinetics and pharmacodynamics of medications, pharmacogenomics research aims to elucidate these polygenic determinants of drug effects. The ultimate goal is to provide new strategies for optimizing drug therapy based on each patient's genetic determinants of drug efficacy and toxicity. This chapter provides an overview of the current pharmacogenomics literature and offers insights for the potential impact of this field on the safe and effective use of medications.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.genom.2.1.9
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  • 7
    Electronic Resource
    Electronic Resource
    PHARMACOGENOMICS: Unlocking the Human Genome for Better Drug Therapy (2001)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Pharmacology 41 (2001), S. 101-121 
    Details
    ISSN: 0362-1642
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Medicine , Chemistry and Pharmacology
    Notes: Abstract There is great heterogeneity in the way humans respond to medications, often requiring empirical strategies to find the appropriate drug therapy for each patient (the "art" of medicine). Over the past 50 years, there has been great progress in understanding the molecular basis of drug action and in elucidating genetic determinants of disease pathogenesis and drug response. Pharmacogenomics is the burgeoning field of investigation that aims to further elucidate the inherited nature of interindividual differences in drug disposition and effects, with the ultimate goal of providing a stronger scientific basis for selecting the optimal drug therapy and dosages for each patient. These genetic insights should also lead to mechanism-based approaches to the discovery and development of new medications. This review highlights the current status of work in this field and addresses strategies that hold promise for future advances in pharmacogenomics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.pharmtox.41.1.101
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  • 8
    Electronic Resource
    Electronic Resource
    PHARMACOGENOMICS OF ACUTE LEUKEMIA (2006)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Pharmacology 46 (2006), S. 317-353 
    Details
    ISSN: 0362-1642
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Medicine , Chemistry and Pharmacology
    Notes: Over the past four decades, treatment of acute leukemia in children has made remarkable progress, from this disease being lethal to now achieving cure rates of 80% for acute lymphoblastic leukemia and 45% for acute myeloid leukemia. This progress is largely owed to the optimization of existing treatment modalities rather than the discovery of new agents. However, the annual number of patients with leukemia who experience relapse after initial therapy remains greater than that of new cases of most childhood cancers. The aim of pharmacogenetics is to develop strategies to personalize medications and tailor treatment regimens to individual patients, with the goal of enhancing efficacy and safety through better understanding of the person's genetic makeup. In this review, we summarize recent pharmacogenomic studies related to the treatment of pediatric acute leukemia. These include work using candidate-gene approaches, as well as genome-wide studies using haplotype mapping and gene expression profiling. These strategies illustrate the promise of pharmacogenomics to further advance the treatment of human cancers, with childhood leukemia serving as a paradigm.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.pharmtox.45.120403.100018
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  • 9
    Electronic Resource
    Electronic Resource
    A New Method for the Purification of the Alcoholate of the Trimer of Hydroxypyruvic Aldehyde (1938)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 60 (1938), S. 1628-1629 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja01274a032
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  • 10
    Electronic Resource
    Electronic Resource
    Memories (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Marine mammal science 10 (1994), S. 0 
    Details
    ISSN: 1748-7692
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1748-7692.1994.tb00402.x
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