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Sterilization with gaseous ethylene oxide: A review of chemical and physical factors (1968)

Ernst, Robert R. ; Doyle, John E.

New York, NY [u.a.] : Wiley-Blackwell

Biotechnology and Bioengineering 10 (1968), S. 1-31

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ISSN: 0006-3592

Keywords: Chemistry ; Biochemistry and Biotechnology

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology

Notes: Although the basic parameters for ethylene oxide sterilization are established, it is sometimes difficult to attain in practice where the principal limiting factor is moisture availability. There are situations which can limit or enhance the dynamics of sterilization. Such factors, if overlooked, could upset experiments and lead to erroneous conclusions, or defeat the sterilization process entirety. Such are, namely: stratification effects, diffusion barriers, moisture-reducing effects, polymerization, and temperature distribution gradients.

Additional Material: 25 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/bit.260100102

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