ISSN:
0749-1581
Keywords:
3H NMR
;
Exchange rates
;
Kinetic acidity
;
Kinetics
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The first application of tritium NMR spectroscopy to the direct observation of proton-exchange kinetics is described; this technique allows the study of milligram amounts of substrates and for substrates with multiple exchangeable positions. The examples include benzene and the ring and methyl positions of p-xylene reacting with cesium cyclohexylamide in cyclohexylamine, and the enolate positions of cyclohexanone and methyl 7,12-dihydroxy-3-ketocholan-24-oate reacting with heptafluorobutyric acid in dioxane.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1260290517
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