ISSN:
1432-1041
Keywords:
capsaicin
;
ventilation
;
ventilatory drive
;
pulmonary C-fibres
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary Nebulised capsaicin (10−7 M) was inhaled by 8 normal subjects to study its effects on the pattern of breathing. When compared to the diluent alone capsaicin increased mean inspiratory flow, a reflection of central inspiratory drive (mean increase: 25±6%, SEM, p〈0.01), with a trend to increasing ventilation through more rapid but not more shallow breathing. If capsaicin selectively stimulates non-myelinated fibres in the lung in man as it does in dogs, these results suggest that such stimulation in man can alter the pattern of breathing.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00541301
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