Publication Date:
2016-04-17
Description:
Article Human mesenchymal stem cells (hMSC) expressing paracrine factors may enhance therapeutic benefits when transplanted. Here, the authors show that hMSCs stably expressing prostacyclin enhance host regeneration and muscle mass gain in a mouse hindlimb ischaemia model, mediated by the long noncoding RNA H19. Nature Communications doi: 10.1038/ncomms11276 Authors: Yuxiao Deng, Zhongwei Yang, Toya Terry, Su Pan, Darren G. Woodside, Jingxiong Wang, Kehe Ruan, James T. Willerson, Richard A. F. Dixon, Qi Liu
Electronic ISSN:
2041-1723
Topics:
Biology
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Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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