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  • 1
    Keywords: Pharmaceutical chemistry. ; Pharmacology. ; Clinical biochemistry. ; Pharmaceutics. ; Pharmacology. ; Medical Biochemistry.
    Description / Table of Contents: Route-Specific Challenges in the Delivery of Poorly Water-Soluble Drugs -- Optimizing the Formulation of Poorly Water-Soluble Drugs -- Solid-State Techniques for Improving Solubility -- Mechanical Particle-Size Reduction Techniques -- Co-solvent and Complexation Systems -- Injectable Formulations of Poorly Water-Soluble Drugs -- Lipid-Based Formulations -- Structured Development Approach for Amorphous Systems -- Melt Extrusion -- Spray-Drying Technology -- Pharmaceutical Cryogenic Technologies -- Precipitation Technologies for Nanoparticle Production -- Emerging Technologies to Increase the Bioavailability of Poorly Water-Soluble Drugs -- Scientific and Regulatory Considerations for Development and Commercialization of Poorly Water-Soluble Drugs.
    Abstract: The objective of this third edition is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at a minimum a working knowledge of each of the above mentioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop. Highlights the most recent advancements reported in the literature on technologies to improve the dissolution and bioavailability of poorly water soluble drugs Provides a comprehensive discussion of new technologies developed and recently over 40% updated new content Essential read for scientists and researchers in pharmaceutical, chemical, and agricultural industries since over 80% of newly discovered drugs are poorly water soluble.
    Type of Medium: Online Resource
    Pages: XII, 693 p. 280 illus., 138 illus. in color. , online resource.
    Edition: 3rd ed. 2022.
    ISBN: 9783030887193
    Series Statement: AAPS Advances in the Pharmaceutical Sciences Series, 50
    DDC: 615.19
    Language: English
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  • 2
    Keywords: Freshwater ecology. ; Marine ecology. ; Animal culture. ; Biotic communities. ; Physical geography. ; Evolution (Biology). ; Freshwater and Marine Ecology. ; Animal Science. ; Ecosystems. ; Earth System Sciences. ; Evolutionary Theory.
    Description / Table of Contents: Introduction: the Habitat and the Ecosystem -- Shallow Hardbottom of East Florida and the Caribbean and the Regional Shelf Setting -- Macroalgae and Cyanobacteria -- Invertebrates -- Fish Assemblages -- Marine Turtles -- Functional Ecological Attributes of Shallow Hardbottom -- Mitigating Shallow Hardbottom Impacts -- Literature Cited -- Appendices.
    Abstract: Nearshore hardbottom reefs of Florida’s east coast are used by over 1100 species of fishes, invertebrates, algae, and sea turtles. These rocky reefs support reproduction, settlement, and habitat use, and are energy sources and sinks. They are also buried by beach renourishment projects in which artificial reefs are used for mitigation. This comprehensive book is for research scientists and agency personnel, yet accessible to interested laypersons including beachfront residents and water-users. An unprecedented collection of research information and often stunning color photographs are assembled including over 1250 technical citations and 127 figures. These shallow reefs are part of a mosaic of coastal shelf habitats including estuarine seagrasses and mangroves, and offshore coral reefs. These hardbottom habitats are federally designated as Essential Fish Habitats - Habitats of Particular Concern and are important feeding areas for federally-protected sea turtles. Organismal and assemblage responses to natural and man-made disturbances, including climate change, are examined in the context of new research and management opportunities for east Florida’s islands in the sand. .
    Type of Medium: Online Resource
    Pages: XVIII, 472 p. 135 illus., 125 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030403577
    DDC: 577.6
    Language: English
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  • 3
    Series available for loan
    Series available for loan
    Hanover, NH : U.S. Army Cold Regions Research and Engineering Laboratory
    Associated volumes
    Call number: ZSP-201-79/18
    In: CRREL Report, 79-18
    Description / Table of Contents: Temperatures of the subgrade and of sulfur foam insulation test sections in an expedient road were monitored with thermocouples to document freezing and thawing conditions. Vehicular trafficking was conducted on a limited basis to determine the load supporting capabilities of the foam. The sulfur foam, placed directly under a prefabri­cated surface mat, was found to be unsuitable for use as an expedient thermal insulation and traffic load supporting material primarily because of its low tensile strength and high brittleness. The insulating value of sulfur foam pro­duced by the batch process in the field was about one-half that of extruded polystyrene, meaning double the thick­ness for equal protection against thaw.
    Type of Medium: Series available for loan
    Pages: v, 21 Seiten
    Series Statement: CRREL Report 79-18
    Language: English
    Note: CONTENTS Preface Conversion factors: U.S. customary to metric units of measurement Introduction Site preparation Sulfur foam application Sulfur foaming equipment Environmental aspects Traffic testing and test pad observations Field sampling and temperature readings during pouring Lab tests for physical properties Sulfur foam odor analysis Insulation costs Lab experiments with sulfur foam Conclusions Literature cited
    Location: AWI Archive
    Branch Library: AWI Library
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  • 4
    Monograph available for loan
    Monograph available for loan
    [s.l.] : United States Environmental Protection Agency, Office of Policy, Planning, and Evaluation
    Call number: MOP 47402
    Type of Medium: Monograph available for loan
    Location: MOP - must be ordered
    Branch Library: GFZ Library
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  • 5
    Monograph available for loan
    Monograph available for loan
    Cheltenham, UK : Edward Elgar Publishing
    Call number: PIK N 072-18-91856
    Type of Medium: Monograph available for loan
    Pages: xxiv, 732 Seiten
    ISBN: 9781783477609 , 9781783477616 (electronic)
    Series Statement: Elgar Encyclopedia of Environmental Law Volume 1
    Language: English
    Note: Contents: Foreword to the Encyclopedia ; Foreword to Volume 1 ; Introduction to Volume 1 ; PART I GENERAL THEMES The Goals of Climate Policy ; 1. The Science of Climate Change: A Legal Perspective on the IPCC ; 2. The Precautionary Principle and Climate Change ; 3. Setting the Social Cost of Carbon ; 4. Human Rights and Climate Change: Building Synergies for a Common Future ; Approaches to Addressing Climate Change ; 5. Climate Policy Instrument Choices ; 6. Corporate Social Responsibility and Climate Change ; 7. Local Authorities and Climate Change ; 8. Individual Behaviour, The Social Sciences and Climate Change ; 9. Criminal Law and Climate Change ; 10. Research and Scholarship on Climate Change Law in Developing Countries ; PART II INTERNATIONAL LAW PERSPECTIVE General Issues ; 11. The Climate as a Global Common ; 12. CBDR and Climate Change ; 13. The Potential Roles of the ICJ in Climate Change-related Claims ; 14. Unilateralism, Extraterritoriality and Climate Change ; 15. Climate Engineering and International Law ; 16. Carbon Capture and Storage as a Bridging Technology ; Treaties Related to Climate Change ; The UN Negotiation Process ; 17. The United Nations Framework Convention on Climate Change: A Framework Approach to Climate Change ; 18. The UNFCCC: Legal Scholarship in Four Key Areas ; 19. The Kyoto Protocol, With a Special Focus on the Flexible Mechanisms ; 20. The Kyoto Protocol’s Compliance Mechanism ; 21. REDD+ as a Climate Change Mitigation Mechanism ; 22. International Treaty Fragmentation and Climate Change ; Alternative International Approaches ; 23. ICAO and IMO: International Sectoral Approaches to Greenhouse Gas Reductions in Transport ; 24. Interlinkages Between Climate Change, Ozone Depletion and Air Pollution: The International Legal Framework ; 25. The WTO and Climate Change ; 26. Climate Change and International Investment Treaties ; PART III NATIONAL AND REGIONAL PERSPECTIVES ON REDUCING GREENHOUSE GASES General Issues ; 27. Polycentrism and Climate Change ; 28. Climate Change Federalism ; 29. Environmental Impact Assessments and Climate Change ; 30. The Role of the National Courts in GHG Emissions Reductions ; Regional and National Mitigation Approaches ; Emissions Trading ; 31. Greenhouse Gas Emissions Trading in the EU ; 32. North American Greenhouse Gas Emission Trading Systems ; 33. Emissions Trading in China ; Other Regulatory Approaches to Reduce Greenhouse Gases ; 34. Traditional Regulation’s Role in Greenhouse Gas Abatement ; 35. Carbon Taxes ; 36. Transportation as a Climate Wedge and Challenge under United States Law ; 37. Biofuel ; 38. Renewable Energy: Support Mechanisms ; 39. Renewable Energy: Public Acceptance and Citizens’ Financial Participation ; 40. Energy Efficiency and Conservation ; Mitigation Strategies in Developing Countries ; 41. India’s Climate Change Mitigation Strategy ; 42. Green Growth Policy in Korea ; PART IV ADAPTATION Specific Impacts and Sectors ; 43. Integrated Water Law and Climate Change: An EU Perspective ; 44. Water Availability and Allocation ; 45. Managing Ecosystem Effects in an Era of Rapid Climate Change ; 46.Ocean Adaptation ; 47. Coastal Issues ; 48. Adaptation and the Energy Sector ; Cross-cutting Issues and Adaptation Techniques ; 49. Adaptation Justice ; 50. Loss and Damage in the UN Climate Regime ; 51. Indigenous Peoples and Climate Change ; 52. Human Mobility and Climate Change ; 53. Urban Planning and Climate Change ; 54. Insurance ; 55. Disaster Law and Climate Change ; PART V CONCLUSIONS 56. The Emergence of Global Climate Law
    Location: A 18 - must be ordered
    Branch Library: PIK Library
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  • 6
    Publication Date: 2023-04-03
    Description: As in most disciplines of science, technology, engineering, mathematics and medicine (STEMM), gender disparity is prevalent in the ranking of Earth Sciences faculties at senior and advanced levels. (i.e., Associate and Full Professors). In this study, a robust database was mined, created, and analyzed to assess the faculty compositions of 142 Earth Science departments in 39 countries across Africa. The data were collected from verifiable online resources focusing on ranks and gender ratios within each department. The studied earth science departments cut across universities in northern, southern, central, eastern, and western Africa. Our data revealed that female faculty members are predominantly underrepresented in most of the departments documented and are markedly uncommon in senior positions such as Professors, associate Professors, and senior researchers compared to their male counterparts. On the contrary, female faculty members are predominant in the lower cadres, such as lecturers, teaching, and graduate assistants. The observed male to female ratio is 4:1. At the base of this gender gap is the lower enrolment of female students in Earth Science courses from undergraudate to graduate studies. To achieve gender equality in Earth Science faculty composition in Africa, we recommend increasing female students' enrollment, mentoring, awareness, timely promotion of accomplished female researchers, and formulation of enabling government policies. More work-related policies that guarantee work-life balance for female earth science academic professionals should be formulated to attract and retain more women into Earth Sciences careers.
    Type: info:eu-repo/semantics/article
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  • 7
    Keywords: Canada, Politique sociale. ; Canada, Social policy. ; Chile, Social policy. ; Chili, Politique sociale. ; Ghana, Social policy. ; Ghāna, Politique sociale. ; Développement durable. ; Politique sociale. ; Social policy. ; Sustainable development.
    Notes: Preface / Daniel A. Morales-Gómez -- Ch. 1. Introduction: the paradox of development / Necla Tschirgi -- Ch. 2. Ghana: social-policy reform in Africa / Ernest Aryeetey and Markus Goldstein -- Ch. 3. Chile: progress, problems, and prospects / Dagmar Raczynski -- Ch. 4. Canada: experience and lessons for the future / Terrance Hunsley -- Ch. 5. Conclusion: a research agenda for social-policy reform / Jennifer L. Moher -- Appendix 1: Acronyms and abbreviations -- Appendix 2: Contributing authors -- Bibliography
    Pages: viii, 160, [1] p.
    ISBN: 1-552-50047-0
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  • 8
    Unknown
    Albany : State University of New York Press
    SUNY series in philosophy  
    Keywords: Hartshorne, Charles,, 1897-2000, Contributions to doctrine of God. ; Hartshorne, Charles,, 1897-, Et la doctrine de Dieu. ; Dieu. ; Dieu, Histoire des doctrines, 20e siècle. ; God. ; God, History of doctrines, 20th century. ; Process theology. ; Theism. ; Théisme. ; Théologie du devenir.
    Pages: xi, 247 p.
    ISBN: 0-585-04281-0
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  • 9
    Publication Date: 2024-04-04
    Description: This volume presents new research by the Topoi group "The Conception of Spaces in Language" on the expression of spatial relations in ancient languages. The six articles in this volume discuss static and dynamic aspects of the spatial grammars of Ancient to Medieval Greek, Akkadian, Hittite, and Hieroglyphic Ancient Egyptian, as well as field data on eight modern languages (Arabic, Hebrew, English, German, Russian, French, Italian, and Spanish). Among the grams discussed are spatial particles, motion verbs, case and, most prominently, spatial prepositions. All ancient language data are fully explained in linguistic word-by-word glosses and are therefore accessible to scholars who are not themselves experts on the respective languages. Taken together, these contributions extend the scope of research on spatial grammar back to the third millennium BCE.
    Keywords: P ; D51-90 ; Linguistics of space ; motion verbs ; case ; adpositions ; thema EDItEUR::P Mathematics and Science
    Language: English
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  • 10
    Publication Date: 2024-04-05
    Description: Coastal wetlands such as mangrove forests and saltmarshes provide a range of important benefits to people, broadly defined as ecosystem services. These include provisioning services such as fuelwood and food, regulating services such as carbon sequestration and wave attenuation, and various tangible and intangible cultural services. However, strong negative perceptions of coastal wetlands also exist, often driven by the perceived or actual ecosystem disservices that they also produce. These can include odour, a sense of danger, and their real or perceived role in vector and disease transmission (e.g., malaria). This review provides an introduction to the ecosystem services and disservices concepts, and highlights the broad range of services and disservices provided by mangrove forests and saltmarshes. Importantly, we discuss the key implications of ecosystem services and disservices for the management of these important coastal ecosystems. Ultimately, a clear binary does not exist between ecosystem services and disservices; an ecosystem service to one stakeholder can be viewed as a disservice to another, or a service can change seasonally into a disservice, and vice versa. It is not enough to only consider the beneficial ecosystem services that coastal wetlands provide: instead, we need to provide a balanced view of coastal wetlands that incorporates the complexities that exist in how humans relate to and interact with these important coastal ecosystems.
    Keywords: Volume, Todd, Swearer, Smith, S, Russell, Review, P, OMBAR, Oceanography, Marine, L, I, Hawkins, Firth, Evans, Biology, Bates,B, Annual, Allcock ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSP Hydrobiology::PSPM Marine biology
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