Publication Date:
1980-10-31
Description:
A method devised for conjugating liposomes with protein resulted in the binding of up to 200 micrograms of immunoglobulin G per micromole of lipid. The coupling of antibody to human erythrocyte F(ab')2 in vesicles (140 molecules per vesicle) by this method caused a 200-fold increase in the binding of vesticles to human erythrocytes and resulted in about 80 percent of the vesicle lipid and contents being associated with cells.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Heath, T D -- Fraley, R T -- Papahdjopoulos, D -- CA 25526-01/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 1980 Oct 31;210(4469):539-41.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7423203" target="_blank"〉PubMed〈/a〉
Keywords:
Antigen-Antibody Complex
;
Erythrocyte Membrane/immunology
;
Humans
;
*Immunoglobulin Fab Fragments
;
In Vitro Techniques
;
*Isoantibodies
;
Liposomes/*administration & dosage
;
Membrane Lipids
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
Permalink
