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  • 1
    Publication Date: 2005-10-29
    Description: The 20-year, U.S. $4 billion-dollar international effort to eradicate wild polioviruses now includes monovalent oral poliovirus type 1 vaccine (mOPV1), which was first given to 40 million children in India in April 2005. As this vaccine is being introduced to eliminate some of the last poliovirus reservoirs, the Global Polio Eradication Initiative is planning for the eventual synchronized worldwide cessation of the routine use of all oral poliovirus vaccines (OPVs) because of their capacity to cause, rarely, outbreaks of paralytic poliomyelitis. This Policy Forum reviews the feasibility and implications of eventually stopping the use of live polio vaccines.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Aylward, R Bruce -- Sutter, Roland W -- Heymann, David L -- New York, N.Y. -- Science. 2005 Oct 28;310(5748):625-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Global Polio Eradication Initiative, World Health Organization, Geneva 27 Switzerland. aylwardb@who.int〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/16254173" target="_blank"〉PubMed〈/a〉
    Keywords: Drug Utilization/legislation & jurisprudence ; Global Health ; Health Policy ; Humans ; Legislation, Drug ; Mass Vaccination/legislation & jurisprudence/organization & administration ; Poliomyelitis/*prevention & control ; *Poliovirus Vaccine, Oral ; Public Health
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1998-03-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Williams, R J -- Heymann, D L -- New York, N.Y. -- Science. 1998 Feb 20;279(5354):1153-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Emerging and Other Communicable Diseases Surveillance and Control, World Health Organization (WHO), Geneva, Switzerland. williamsr@who.ch〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9508688" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Anti-Bacterial Agents/administration & dosage/*therapeutic use ; Cross Infection/epidemiology/prevention & control ; Developed Countries ; Developing Countries ; Drug Prescriptions ; *Drug Resistance, Microbial ; Drug Utilization ; Drug and Narcotic Control ; Education, Medical, Continuing ; Health Education ; Humans ; Infection/diagnosis/*drug therapy
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
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    Nature Publishing Group (NPG)
    Publication Date: 2014-10-17
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Heymann, David L -- England -- Nature. 2014 Oct 16;514(7522):299-300. doi: 10.1038/514299a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/25318509" target="_blank"〉PubMed〈/a〉
    Keywords: Africa, Western/epidemiology ; Cities/epidemiology ; *Clinical Trials as Topic/ethics ; Congo/epidemiology ; *Contact Tracing ; Cross Infection/epidemiology ; Disease Outbreaks/prevention & control/statistics & numerical data ; Fever/diagnosis ; Funeral Rites ; *Hemorrhagic Fever, Ebola/diagnosis/epidemiology/prevention & ; control/therapy/transmission ; History, 20th Century ; History, 21st Century ; Humans ; Plasmapheresis/utilization ; Protective Clothing ; *Quarantine ; Rural Population/statistics & numerical data ; Survivors ; Time Factors ; Urban Population/statistics & numerical data ; World Health Organization
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 4
    Publication Date: 2012-01-17
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fouchier, Ron -- Osterhaus, A B -- Steinbruner, John -- Yuen, Kwok-Yung -- Henderson, D A -- Klotz, Lynn -- Sylvester, Ed -- Taubenberger, Jeffery K -- Ebright, Richard H -- Heymann, David L -- England -- Nature. 2012 Jan 15;481(7381):257-9. doi: 10.1038/481257a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22246325" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Bioterrorism/*prevention & control ; Birds/virology ; Civil Defense/methods ; Confidentiality ; Global Health/statistics & numerical data ; Guidelines as Topic ; Hong Kong/epidemiology ; Host Specificity ; Humans ; Influenza A Virus, H1N1 Subtype/genetics/pathogenicity ; Influenza A Virus, H5N1 Subtype/genetics/*pathogenicity ; Influenza Vaccines/supply & distribution ; Influenza, Human/mortality/*transmission/*virology ; *International Cooperation ; Laboratory Infection/prevention & control ; Pandemics/*prevention & control/statistics & numerical data ; *Publishing/standards ; Variola virus ; World Health Organization
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 5
    Publication Date: 2006-11-18
    Description: The feasibility of global polio eradication is being questioned as a result of continued transmission in a few localities that act as sources for outbreaks elsewhere. Perhaps the greatest challenge is in India, where transmission has persisted in Uttar Pradesh and Bihar despite high coverage with multiple doses of vaccine. We estimate key parameters governing the seasonal epidemics in these areas and show that high population density and poor sanitation cause persistence by not only facilitating transmission of poliovirus but also severely compromising the efficacy of the trivalent vaccine. We analyze strategies to counteract this and show that switching to monovalent vaccine may finally interrupt virus transmission.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Grassly, Nicholas C -- Fraser, Christophe -- Wenger, Jay -- Deshpande, Jagadish M -- Sutter, Roland W -- Heymann, David L -- Aylward, R Bruce -- New York, N.Y. -- Science. 2006 Nov 17;314(5802):1150-3.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Infectious Disease Epidemiology, Imperial College London, Norfolk Place, London, UK. n.grassly@imperial.ac.uk〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17110580" target="_blank"〉PubMed〈/a〉
    Keywords: Child ; Disease Outbreaks/*prevention & control ; Dose-Response Relationship, Immunologic ; Humans ; Immunization Programs ; India/epidemiology ; Poliomyelitis/epidemiology/*prevention & control ; Poliovirus Vaccine, Oral/*administration & dosage/chemistry ; Population Density ; Sanitation
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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