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  • 1
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    A human genome diversity cell line panel (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-04-17
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cann, Howard M -- de Toma, Claudia -- Cazes, Lucien -- Legrand, Marie-Fernande -- Morel, Valerie -- Piouffre, Laurence -- Bodmer, Julia -- Bodmer, Walter F -- Bonne-Tamir, Batsheva -- Cambon-Thomsen, Anne -- Chen, Zhu -- Chu, J -- Carcassi, Carlo -- Contu, Licinio -- Du, Ruofu -- Excoffier, Laurent -- Ferrara, G B -- Friedlaender, Jonathan S -- Groot, Helena -- Gurwitz, David -- Jenkins, Trefor -- Herrera, Rene J -- Huang, Xiaoyi -- Kidd, Judith -- Kidd, Kenneth K -- Langaney, Andre -- Lin, Alice A -- Mehdi, S Qasim -- Parham, Peter -- Piazza, Alberto -- Pistillo, Maria Pia -- Qian, Yaping -- Shu, Qunfang -- Xu, Jiujin -- Zhu, S -- Weber, James L -- Greely, Henry T -- Feldman, Marcus W -- Thomas, Gilles -- Dausset, Jean -- Cavalli-Sforza, L Luca -- New York, N.Y. -- Science. 2002 Apr 12;296(5566):261-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11954565" target="_blank"〉PubMed〈/a〉
    Keywords: *Biological Specimen Banks ; *Cell Line ; Continental Population Groups/genetics ; DNA/genetics ; Databases, Factual ; Female ; *Genetic Variation ; *Genome, Human ; Haplotypes ; Humans ; Informed Consent ; *Lymphocytes ; Male ; Polymorphism, Single Nucleotide
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    The genome-wide structure of the Jewish people (2010)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2010-06-10
    Description: Contemporary Jews comprise an aggregate of ethno-religious communities whose worldwide members identify with each other through various shared religious, historical and cultural traditions. Historical evidence suggests common origins in the Middle East, followed by migrations leading to the establishment of communities of Jews in Europe, Africa and Asia, in what is termed the Jewish Diaspora. This complex demographic history imposes special challenges in attempting to address the genetic structure of the Jewish people. Although many genetic studies have shed light on Jewish origins and on diseases prevalent among Jewish communities, including studies focusing on uniparentally and biparentally inherited markers, genome-wide patterns of variation across the vast geographic span of Jewish Diaspora communities and their respective neighbours have yet to be addressed. Here we use high-density bead arrays to genotype individuals from 14 Jewish Diaspora communities and compare these patterns of genome-wide diversity with those from 69 Old World non-Jewish populations, of which 25 have not previously been reported. These samples were carefully chosen to provide comprehensive comparisons between Jewish and non-Jewish populations in the Diaspora, as well as with non-Jewish populations from the Middle East and north Africa. Principal component and structure-like analyses identify previously unrecognized genetic substructure within the Middle East. Most Jewish samples form a remarkably tight subcluster that overlies Druze and Cypriot samples but not samples from other Levantine populations or paired Diaspora host populations. In contrast, Ethiopian Jews (Beta Israel) and Indian Jews (Bene Israel and Cochini) cluster with neighbouring autochthonous populations in Ethiopia and western India, respectively, despite a clear paternal link between the Bene Israel and the Levant. These results cast light on the variegated genetic architecture of the Middle East, and trace the origins of most Jewish Diaspora communities to the Levant.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Behar, Doron M -- Yunusbayev, Bayazit -- Metspalu, Mait -- Metspalu, Ene -- Rosset, Saharon -- Parik, Juri -- Rootsi, Siiri -- Chaubey, Gyaneshwer -- Kutuev, Ildus -- Yudkovsky, Guennady -- Khusnutdinova, Elza K -- Balanovsky, Oleg -- Semino, Ornella -- Pereira, Luisa -- Comas, David -- Gurwitz, David -- Bonne-Tamir, Batsheva -- Parfitt, Tudor -- Hammer, Michael F -- Skorecki, Karl -- Villems, Richard -- England -- Nature. 2010 Jul 8;466(7303):238-42. doi: 10.1038/nature09103. Epub 2010 Jun 9.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Molecular Medicine Laboratory, Rambam Health Care Campus, Haifa 31096, Israel. behardm@usernet.com〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20531471" target="_blank"〉PubMed〈/a〉
    Keywords: Africa, Northern/ethnology ; Alleles ; Asia ; Chromosomes, Human, Y/genetics ; DNA, Mitochondrial/genetics ; Ethiopia/ethnology ; Europe ; Genome, Human/*genetics ; Genotype ; Geography ; Humans ; India/ethnology ; Jews/classification/*genetics ; Middle East/ethnology ; Phylogeny ; Principal Component Analysis
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Nature Publishing Group (NPG)
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  • 3
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    Biomarkers: better donor protection (2011)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2011-02-11
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gurwitz, David -- England -- Nature. 2011 Feb 10;470(7333):175. doi: 10.1038/470175c.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21307923" target="_blank"〉PubMed〈/a〉
    Keywords: Biological Specimen Banks/*standards ; *Biomarkers ; Databases, Genetic/ethics/legislation & jurisprudence/standards ; Genetic Privacy/ethics/*legislation & jurisprudence/*standards ; Humans ; *Internationality ; Prejudice ; *Tissue Donors
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Nature Publishing Group (NPG)
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  • 4
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    Parental consent: Guarding children's genetic privacy (2013)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2013-03-01
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lunshof, Jeantine E -- Gurwitz, David -- England -- Nature. 2013 Feb 28;494(7438):430. doi: 10.1038/494430d.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23446408" target="_blank"〉PubMed〈/a〉
    Keywords: *Databases, Genetic ; *Genetic Privacy ; Genome, Human/*genetics ; Humans ; Male
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Nature Publishing Group (NPG)
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  • 5
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    Computing: Keep files small to curb energy use (2014)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2014-10-17
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gurwitz, David -- England -- Nature. 2014 Oct 16;514(7522):305. doi: 10.1038/514305b.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Tel-Aviv University, Israel.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/25318514" target="_blank"〉PubMed〈/a〉
    Keywords: Computer Communication Networks/*economics ; Conservation of Energy Resources/economics/*methods ; Costs and Cost Analysis ; Electronic Mail/economics ; Internet/*economics/utilization ; Periodicals as Topic/economics ; Publishing/economics ; Research/economics
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Nature Publishing Group (NPG)
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  • 6
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    Research ethics. Children and population biobanks (2009)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2009-08-15
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gurwitz, David -- Fortier, Isabel -- Lunshof, Jeantine E -- Knoppers, Bartha Maria -- New York, N.Y. -- Science. 2009 Aug 14;325(5942):818-9. doi: 10.1126/science.1173284.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉National Laboratory for the Genetics of Israeli Populations, Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, 69978, Israel. gurwitz@post.tau.ac.il〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19679798" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Biological Specimen Banks/*ethics/standards ; Biomedical Research/*ethics ; Child ; *Dna ; Databases, Nucleic Acid/*ethics/standards ; Genetic Privacy ; Genetic Research/*ethics ; Humans ; Information Dissemination ; *Informed Consent ; Public Policy
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 7
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    Data re-identification: protect the children (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-03-02
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gurwitz, David -- New York, N.Y. -- Science. 2013 Mar 1;339(6123):1033. doi: 10.1126/science.339.6123.1033-a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23449578" target="_blank"〉PubMed〈/a〉
    Keywords: Biomedical Research/*ethics ; Genetic Privacy/*ethics ; Genomics/*ethics ; Human Genome Project/*ethics ; Humans ; Information Dissemination/*ethics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 8
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    Gene drives raise dual-use concerns (2014)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2014-08-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gurwitz, David -- New York, N.Y. -- Science. 2014 Aug 29;345(6200):1010. doi: 10.1126/science.345.6200.1010-b.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel. gurwitz@post.tau.ac.il.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/25170142" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Animals, Genetically Modified/*genetics ; *Clustered Regularly Interspaced Short Palindromic Repeats ; Communicable Disease Control/*methods ; Culicidae/*genetics ; *Gene Expression Regulation ; Genetic Engineering/*methods ; Humans ; Mosquito Control/*methods
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 9
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    Genetic privacy: trust is not enough (2015)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2015-02-28
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gurwitz, David -- New York, N.Y. -- Science. 2015 Feb 27;347(6225):957-8. doi: 10.1126/science.347.6225.957-b.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, 69978, Israel. gurwitz@post.tau.ac.il.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/25722403" target="_blank"〉PubMed〈/a〉
    Keywords: *Biomedical Research ; *Confidentiality ; *Genetic Privacy ; Humans ; *Information Dissemination ; *Research Subjects ; *Trust
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 10
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    SIRT1 , miR-132 and miR-212 link human longevity to Alzheimer’s Disease (2018)
    Springer Nature
    Details
    Publication Date: 2018-06-01
    Description: SIRT1 , miR-132 and miR-212 link human longevity to Alzheimer’s Disease 〈i〉SIRT1〈/i〉, miR-132 and miR-212 link human longevity to Alzheimer’s Disease, Published online: 31 May 2018; doi:10.1038/s41598-018-26547-6 SIRT1 , miR-132 and miR-212 link human longevity to Alzheimer’s Disease
    Electronic ISSN: 2045-2322
    Topics: Natural Sciences in General
    Published by Springer Nature
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