Publication Date:
2015-04-17
Description:
Article Macrophages activate gene expression of alternative activation program in response to IL-13. Here the authors show that Liver Receptor Homologue-1 regulates synthesis of lipid metabolites stimulating antifungal and repressing proinflammatory genes in macrophages exposed to IL-13 through PPAR activation. Nature Communications doi: 10.1038/ncomms7801 Authors: Lise Lefèvre, Hélène Authier, Sokrates Stein, Clarisse Majorel, Bettina Couderc, Christophe Dardenne, Mohamad Ala Eddine, Etienne Meunier, José Bernad, Alexis Valentin, Bernard Pipy, Kristina Schoonjans, Agnès Coste
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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