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  • 1
    Electronic Resource
    Electronic Resource
    Three-Dimensional Microfabrication System for Scaffolds in Tissue Engineering (2006)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 326-328 (Dec. 2006), p. 723-726 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Understanding chondrocyte behavior inside complex, three-dimensional environmentswith controlled patterning of geometrical factors would provide significant insights into the basicbiology of tissue regenerations. One of the fundamental limitations in studying such behavior hasbeen the inability to fabricate controlled 3D structures. To overcome this problem, we havedeveloped a three-dimensional microfabrication system. This system allows fabrication ofpredesigned internal architectures and pore size by stacking up the photopolymerized materials.Photopolymer SL5180 was used as the 3D microfabricated scaffolds. The results demonstrate thatcontrollable and reproducible inner-architecture can be fabricated. Chondrocytes from human nasalseptum were cultured in 3D scaffolds for cell adhesion behavior. Such 3D scaffolds might provideeffective key factors to study cell behavior in complex environments and could eventually lead tooptimum design of scaffolds in various tissue regenerations such as cartilage, bone, etc. in a nearfuture
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/52/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.326-328.723.pdf
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  • 2
    Electronic Resource
    Electronic Resource
    Development of Micro-Patterned 2.5-D Scaffold Using Micro-End-Milling (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 342-343 (July 2007), p. 53-56 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: We fabricated micro-patterned 2.5-D scaffolds using micro-end-milling with controlledpore and island sizes and interconnectivity to determine the effects of the micro-patterns on the cellculturing process. Micro-end-milling can easily realize a high aspect ratio and accuracy, and can beapplied to various materials, including those that are biocompatible and biodegradable. Sixteentypes of micro-patterned scaffolds were designed and fabricated using the micro-end-millingprocess. Fibroblasts were seeded and cultured to examine the viability of the developed micropatternedscaffolds and their absorbed cell adhesion. The results confirmed that the fabricatedmicro-patterns functioned successfully as scaffolds
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/54/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.342-343.53.pdf
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  • 3
    Electronic Resource
    Electronic Resource
    Scaffold Fabrication with Biodegradable Poly(propylene fumarate) Using Microstereolithography (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 342-343 (July 2007), p. 141-144 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Although tissue engineering is an area with great potential, it still has few applicationsdue to the lack of biocompatible, biodegradable materials with suitable mechanical properties.Recently, several biodegradable materials were developed, of which poly(propylene fumarate (PPF)is one of the most notable. It degrades into fumaric acid and propylene glycol, which are bothbiocompatible products. Microstereolithography is a new technology that can be used to fabricatefree-form 3-D microstructures by dividing a desired shape into many slices of a given horizontalthickness. This technology requires a low-viscosity resin to fabricate fine structures. However, theviscosity of PPF is too high to fabricate 3D structures using microstereolithography. Therefore, wereduced the viscosity of the resin by adding diethyl fumarate (DEF). Then, we added aphotoinitiator to photo-crosslink the DEF/PPF resin, and fabricated 2.5-D scaffolds using oursystem. We confirmed that microstereolithography technology is effective in scaffold fabrication.The fabricated 2.5-D scaffolds were seeded with fibroblasts and the cells attached well afterseeding
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/54/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.342-343.141.pdf
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  • 4
    Electronic Resource
    Electronic Resource
    Adaptive modelling of the milling process and application of a neural network for tool wear monitoring (1996)
    Springer
    The international journal of advanced manufacturing technology 12 (1996), S. 5-13 
    Details
    ISSN: 1433-3015
    Keywords: Adaptive signal processing ; Autoregressive time series ; Feature ; Milling process ; Neural network ; Tool wear
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract An adaptive signal processing scheme that uses a low-order autoregressive time series model is introduced to model the cutting force data for tool wear monitoring during face milling. The modelling scheme is implemented using an RLS (recursive least square) method to update the model parameters adaptively at each sampling instant. Experiments indicate that AR model parameters are good features for monitoring tool wear, thus tool wear can be detected by monitoring the evolution of the AR parameters during the milling process. The capability of tool wear monitoring is demonstrated with the application of a neural network. As a result, the neural network classifier combined with the suggested adaptive signal processing scheme is shown to be quite suitable for in-process tool wear monitoring
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01178957
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  • 5
    Electronic Resource
    Electronic Resource
    Calculation of Reference Cutting Force as a Criterion of Rough Milling Using FEM Analysis (2006)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 526 (Oct. 2006), p. 43-48 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: For effective rough milling, an optimized criterion is required to select the feedrate. In thisstudy, a method to obtain the most appropriate reference cutting force for rough milling wasdeveloped. The reference cutting force was determined by considering the transverse rupture strengthof the tool material and the area of the rupture surface. A finite element method analysis wasperformed to accurately calculate the area of the rupture surface. Using the analyzed results, the effectof various cutting parameters on the chipping phenomenon was determined. The calculation methodfor the reference cutting force considered the area of the rupture surface, the effect of the rake angle,and the axial depth of cut. The experimental results clearly show that the reference cutting forceobtained from the proposed method met the desired constraints
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/13/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.526.43.pdf
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  • 6
    Electronic Resource
    Electronic Resource
    The Effect of 3D Construction Culture of Human Chondrocytes Using Alginate Sponge (2006)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 326-328 (Dec. 2006), p. 883-888 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In this study, we investigated the effect of the use of alginate sponge as a chondrocyte-3Dscaffold for the construction of a cartilage graft. Alginate sponge was made by 5% alginic acidwhich was crosslinked by CaCl2. Chondrocytes were obtained from a nasal septum after theoperation and cultured in 3D alginate sponge. For analysis of cell differentiation, we have checkedaggrecan, collagen type I and II using RT-PCR and performed the histological and scanningelectron microscopy analysis. Our experiments showed that alginate sponge of 5% promotedsufficient chondrocyte proliferation and differentiation, resulting in the formation of a specificcartilage matrix. The sponge presents new perspectives with respect to in vitro production of"artificial" cartilage. We conclude that the alginate sponges have potential as a scaffold for cartilagetissue engineering
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/52/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.326-328.883.pdf
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  • 7
    Electronic Resource
    Electronic Resource
    Effect of Three-Dimensional Scaffold Geometry on Chondrocyte Adhesion (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 342-343 (July 2007), p. 97-100 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: This paper compares the characteristics of chondrocyte adhesion on two types of threedimensional(3-D) scaffold: types A and B. These 3-D scaffolds can be repeatedly constructed withthe same dimensions using microstereolithography, a system that allows the fabrication of predesignedinternal structures, such as pore size and porosity, by stacking the photopolymerizedmaterial. In tissue engineering, chondrocyte adhesion to a scaffold should have a major effect on theregeneration of cartilage. In this regard, we evaluated chondrocyte adhesion to two types of scaffoldand found that chondrocyte adhesion was better on the type B scaffold than on the type A,demonstrating the importance of scaffold geometry in chondrocyte adhesion
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/54/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.342-343.97.pdf
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  • 8
    Electronic Resource
    Electronic Resource
    A new certainty grid based mapping and navigation system for an autonomous mobile robot (1995)
    Springer
    The international journal of advanced manufacturing technology 10 (1995), S. 139-148 
    Details
    ISSN: 1433-3015
    Keywords: Bayesian model ; Mapping ; Mobile Robot ; Navigation ; Path planning ; Specular reflection
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract A complete Bayesian derivation for a sensor data updating formula for certainty grids is given, and its validity confirmed in a simulation. In the real world this formula alone is less valid because of the specular reflection effect, which seriously detracts from the map quality. A simple and practical approach, which greatly enhances the map quality in spite of some loss of range information, is proposed to compensate for this. A new path planning method based on the enhanced map is implemented on a mobile robot, and every aspect of the new algorithm is investigated through a series of experiments. The results show the validity and usefulness of the proposed approaches, i.e. updating formulae, specular reflection correction and path planning methods.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01179282
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  • 9
    Electronic Resource
    Electronic Resource
    Proposition for a Volumetric Error Model Considering Backlash in Machine Tools (1999)
    Springer
    The international journal of advanced manufacturing technology 15 (1999), S. 554-561 
    Details
    ISSN: 1433-3015
    Keywords: Key words.Assessment; Backlash error; Machine tool; Volumetric error model
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: This paper proposes a new scheme for evaluating the machine tool volumetric error model including the backlash error. The effects of backlash errors are assessed by experiments, conducted on a three-axis vertical-type machining centre. The assessment was taken for 18 error components out of the 21 geometric errors of a machine tool. It was shown that the backlash error of a machine tool is one of the systematic errors. Some important characteristics of the backlash error were identified; that is, the backlash error is a function of position, it decreases as the feedrate increases, and its size and shape vary according to the machine structure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001700050101
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  • 10
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    Unknown
    Tissue-engineering of vascular grafts containing endothelium and smooth-muscle using triple-coaxial cell printing (2019)
    American Institute of Physics
    Details
    Publication Date: 2019-12-01
    Electronic ISSN: 1931-9401
    Topics: Physics
    Published by American Institute of Physics
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