ISSN:
0021-8383
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Nucleophilic Substitution to Carbonic Acid Derivatives. XVI. Kinetics and Mechanism of N,N,N′-Triphenylchloroformamidin HydrolysisFirst order rate constants of N,N,N′-triphenylchloroformic amidine hydrolysis in dioxane-water have been determined by u.v.-spectroscopy. The effects of water concentration, addition of KClO4, LiCl, HgCl2, and AgNO3 or nucleophilic agents (piperidine) as well as isotopic effects have been investigated. Activation entropy and enthalpy have been determined. According to the data obtained the reaction takes place in two steps - chlorionization and reaction of the formed cation with the nucleophilic agent. Both steps have rates of the same order of magnitude, but can become slow steps in specific conditions.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19823240504
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