ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Hydroxyapatite/chondroitin sulfate (HAp/ChS) microparticles with the perfectlyspherical shape and the averaged particle sizes of 4.1, 7.8, 19.9 and 29.4 µm were fabricated by a spray dry method under the different atomizing pressures and the concentrations of suspensions. The contents of ChS in the microparticles were varied at 1.49, 3.18, 7.82, 14.2 wt%, and the ChS elution rate in distilled water from the microparticles was increased with the increase of ChS contents. The adsorption isotherms of cytochrome C on the microparticles in 1/10 diluted phosphatebuffer saline (PBS) were followed to the Langmuir’s equation regardless of the change of ChS contents, while those of catalase were not followed. The HAp/ChS microparticles can adsorb greater amount of cytochrome C than pure HAp microparticles, but less amount of catalase than pure HAp. The electrostatic interaction between the proteins and ChS was of great importance inthe adsorption properties
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/51/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.309-311.533.pdf
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