ISSN:
1476-5535
Keywords:
CP-61,405
;
Pyrrolether
;
Streptomyces routienii Huang sp. nov.
;
Anticoccidial agent
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Process Engineering, Biotechnology, Nutrition Technology
Notes:
Summary CP-61,405 (C26H29N2O7Na) is a novel polycyclic pyrrolether antibiotic produced by a new species,Streptomyces routienii Huang sp. nov. (ATCC 39446). Recovery, fractionation and purification were achieved using standard procedures. The crystalline form includes the CP-61,405 sodium salt, m.p. 334–335°C, [α] D 25°C +315°C (c=1, chloroform). The structure is shown below. CP-61,405 was co-produced with the polycyclic ether antibiotics salinomycin and epi-17-deoxy-(0–8)-salinomycin. It exhibited activity in vitro against gram-positive and anaerobic bacteria, efficacy against poultry coccidia and stimulation in vitro of propionic acid production.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01569573
Permalink