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  • 1
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The 30S ribosomal subunit has two primary functions in protein synthesis. It discriminates against aminoacyl transfer RNAs that do not match the codon of messenger RNA, thereby ensuring accuracy in translation of the genetic message in a process called decoding. Also, it works with the 50S ...
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  • 2
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Genetic information encoded in messenger RNA is translated into protein by the ribosome, which is a large nucleoprotein complex comprising two subunits, denoted 30S and 50S in bacteria. Here we report the crystal structure of the 30S subunit from Thermus thermophilus, refined to ...
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  • 3
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Yeast 9 (1993), S. 371-378 
    ISSN: 0749-503X
    Keywords: Yeast ; flocculation ; onset ; lectin ; cycloheximide ; heat activation ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: Yeast flocculation involves binding of surface lectins to carbohydrate receptors on neighbouring cell walls. Brewing strains of Saccharomyces cerevisiae normally become flocculent in the stationary phase of growth. This paper presents evidence that lectins are synthesized in exponential phase, inserted into the cell wall, and activated later at the time of flocculation onset.Cycloheximide failed to prevent flocculation unless it was added in early growth; with later additions progressively larger degrees of flocculation occurred. Flocculation onset was delayed by cycloheximide but was otherwise cycloheximide insensitive. Preflocculent cells could be artificially activated to full flocculation by heat. Artificial activation of samples from growing yeast cultures confirmed the progressive synthesis of lectins throughout exponential growth. Pronase E treatment of whole cells prior to heating prevented any activation of flocculation.It was concluded that lectins were synthesized continuously from an early stage of growth and rapidly inserted into the cell wall (accessible by pronase E), where they remained inactive for up to 14 h, before being activated at flocculation onset by an as-yet unknown mechanism. It was found that lectin synthesis and activation occurred in all brewing strains tested.
    Additional Material: 6 Ill.
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  • 4
    ISSN: 0749-503X
    Keywords: Nucleotide metabolism ; a gene family of four ; in-frame insertion ; chromosomal localization ; Candida insectorum ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: Saccharomyces cerevisiae contains at least four PRS genes, all of which have been cloned and sequenced. Each of the four derived amino acid sequences have more than 60% similarity to the corresponding polypeptides of man, rat, Escherichia coli and Salmonella typhimurium. The PRS1 gene maps on chromosome XI, PRS2 on chromosome V, PRS3 on chromosome VIII and PRS4 on chromosome II. One member of this gene family, PRS1, contains a region of non-homology (NHR) shown by cDNA cloning and sequencing not to be an intron. The results presented here suggest that the presence of this NHR is not detrimental to the function of the gene. To date the possibility of protein splicing can be neither proven nor disputed. The sequences submitted to the EMBL data library are available under the following accession numbers: PRS1 (X70069), PRS2 (X74414) and PRS3 (X74415).
    Additional Material: 8 Ill.
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  • 5
    Publication Date: 2022-05-25
    Description: Author Posting. © American Geophysical Union, 2018. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Geochemistry, Geophysics, Geosystems 19 (2018): 3208-3223, doi:10.1029/2018GC007659.
    Description: We performed a detrital zircon (DZ) U‐Pb geochronologic survey of the lower parts of the Danube River approaching its Danube delta, Black Sea sink, and a few large tributaries (Tisza, Jiu, Olt, and Siret) originating in the nearby Carpathian Mountains. Samples are modern sediments. DZ age spectra reflect the geology and specifically the crustal age formation of the source area, which in this case is primarily the Romanian Carpathians and their foreland with contributions from the Balkan Mountains to the south of Danube and the East European Craton. The zircon cargo of these rivers suggests a source area that formed during the latest Proterozoic and mostly into the Cambrian and Ordovician as island arcs and back‐arc basins in a Peri‐Gondwanan subduction setting (~600–440 Ma). The Inner Carpathian units are dominated by a U‐Pb DZ peak in the Ordovician (460–470 Ma) and little inheritance from the nearby continental masses, whereas the Outer Carpathian units and the foreland have two main peaks, one Ediacaran (570–610 Ma) and one in the earliest Permian (290–300 Ma), corresponding to granitic rocks known regionally. A prominent igneous Variscan peak (320–350 Ma) in the Danube's and tributaries DZ zircon record is difficult to explain and points out to either an extra Carpathian source or major unknown gaps in our understanding of Carpathian geology. Younger peaks corresponding to arc magmatism during the Alpine period make up as much as about 10% of the DZ archive, consistent with the magnitude and surface exposure of Mesozoic and Cenozoic arcs.
    Description: Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii (UEFISCDI); Romanian Executive Agency for Higher Education, Research, Development and Innovation Funding Grant Number: PN‐III‐P4‐ID‐PCE‐2016‐0127; U.S. National Science Foundation. Grant Number: EAR 1725002
    Description: 2019-03-14
    Keywords: Danube ; Carpathians ; Detrital zircon ; U‐Pb geochronology ; Continental crust
    Repository Name: Woods Hole Open Access Server
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  • 6
    Publication Date: 2022-05-25
    Description: Author Posting. © American Geophysical Union, 2004. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Tectonics 23 (2004): TC5013, doi:10.1029/2003TC001559.
    Description: The Indus River is the only major drainage in the western Himalaya and delivers a long geological record of continental erosion to the Arabian Sea, which may be deciphered and used to reconstruct orogenic growth if the modern bedload can be related to the mountains. In this study we collected thermochronologic data from river sediment collected near the modern delta. U-Pb ages of zircons spanning 3 Gyr show that only ~5% of the eroding crust has been generated since India-Asia collision. The Greater Himalaya are the major source of zircons, with additional contributions from the Karakoram and Lesser Himalaya. The 39Ar/40Ar dating of muscovites gives ages that cluster between 10 and 25 Ma, differing from those recorded in the Bengal Fan. Biotite ages are generally younger, ranging 0–15 Ma. Modern average exhumation rates are estimated at ~0.6 km/m.y. or less, and have slowed progressively since the early Miocene (~20 Ma), although fission track (FT) dating of apatites may indicate a recent moderate acceleration in rates since the Pliocene (~1.0 km/m.y.) driven by climate change. The 39Ar/40Ar and FT techniques emphasize the dominance of high topography in controlling the erosional flux to the ocean. Localized regions of tectonically driven, very rapid exhumation (e.g., Nanga Parbat, S. Karakoram metamorphic domes) do not dominate the erosional record.
    Description: Scottish Universities Environmental Research Centre (SUERC) is supported by the Scottish Universities and the British National Environmental Research Council (NERC). P. C. wishes to thank the Joint Oceanographic Institutions (JOI) for partial support of this work.
    Keywords: Himalaya ; Indus River ; Fission track ; Exhumation ; Erosion ; Thermochronology
    Repository Name: Woods Hole Open Access Server
    Type: Article
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  • 7
    Publication Date: 2022-10-26
    Description: © The Author(s), 2022. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Jonell, T., Giosan, L., Clift, P., Carter, A., Bretschneider, L., Hathorne, E., Barbarano, M., Garzanti, E., Vezzoli, G., & Naing, T. No modern Irrawaddy River until the late Miocene-Pliocene. Earth and Planetary Science Letters, 584, (2022): 117516, https://doi.org/10.1016/j.epsl.2022.117516.
    Description: The deposits of large Asian rivers with unique drainage geometries have attracted considerable attention due to their explanatory power concerning tectonism, surface uplift and upstream drainage evolution. This study presents the first petrographic, heavy mineral, Nd and Sr isotope geochemistry, and detrital zircon geochronology results from the Holocene Irrawaddy megadelta alongside modern and ancient sedimentary provenance datasets to assess the late Neogene evolution of the Irrawaddy River. Contrary to models advocating a steady post-middle Miocene river, we reveal an evolution of the Irrawaddy River more compatible with regional evidence for kinematic reorganization in Myanmar during late-stage India-Asia collision. Quaternary sediments are remarkably consistent in terms of provenance but highlight significant decoupling amongst fine and coarse fraction 87Sr/86Sr and due to hydraulic sorting. Only well after the late Miocene do petrographic, heavy mineral, isotope geochemistry, and detrital zircon U–Pb results from the trunk Irrawaddy and its tributaries achieve modern-day signatures. The primary driver giving rise to the geometry and provenance signature of the modern Irrawaddy River was regional late Miocene (≤10 Ma) basin inversion coupled with uplift and cumulative displacement along the Sagaing Fault. Middle to late Miocene provenance signatures cannot be reconciled with modern river geometries, and thus require significant loss of headwaters feeding the Chindwin subbasin after ∼14 Ma and the northern Shwebo subbasin after ∼11 Ma. Large-scale reworking after ∼7 Ma is evidenced by modern Irrawaddy River provenance, by entrenchment of the nascent drainage through Plio-Pleistocene inversion structures, and in the transfer of significant sediment volumes to the Andaman Sea.
    Description: TNJ was supported in initial stages of this project by a Postdoctoral Research Fellowship at UQ and software support by LSU. LG thanks support from the Andrew W. Mellon Foundation via Woods Hole Oceanographic Institution. The Charles T. McCord chair at LSU funded coring and detrital zircon U–Pb geochronology essential to the study.
    Keywords: Provenance ; Sediment ; Irrawaddy ; Zircon ; Isotope geochemistry ; Petrography
    Repository Name: Woods Hole Open Access Server
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  • 8
    Publication Date: 2022-05-26
    Description: Author Posting. © The Author(s), 2009. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was published in Tectonophysics 479 (2009): 165-174, doi:10.1016/j.tecto.2008.07.018.
    Description: The Early Ordovician Grampian Orogeny in the British Isles represents a classic example of collision between an oceanic island arc and a passive continental margin, starting around 480 Ma. The South Mayo Trough in western Ireland preserves a complete and well-dated sedimentary record of arc collision. We sampled sandstones and conglomerates from the Rosroe, Maumtrasna and Derryveeny Formations in order to assess erosion rates and patterns during and after arc collision. U-Pb dating of zircons reveals a provenance dominated by erosion from the upper levels of the Dalradian Supergroup (Southern Highland and Argyll Groups), with up to 20% influx from the colliding arc into the Rosroe Formation, but only 6% in the Maumtrasna Formation (~465 Ma). The 24 dominant source regions lay to the northeast (e.g. in the vicinity of the Ox Mountains, 50 km distant, along strike). The older portions of the North Mayo Dalradian and its depositional basement (the Annagh Gneiss Complex) do not appear to have been important sources, while the Connemara Dalradian only plays a part after 460 Ma, when it supplies the Derryveeny Formation. By this time all erosion from the arc had effectively ceased and exhumation rates had slowed greatly. The Irish Grampian Orogeny parallels the modern Taiwan collision in showing little role for the colliding arc in the production of sediment. Negligible volumes of arc crust are lost because of erosion during accretion to the continental margin.
    Keywords: Collision ; Erosion ; Zircon ; Caledonides ; Grampian
    Repository Name: Woods Hole Open Access Server
    Type: Preprint
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  • 9
    Publication Date: 2023-01-13
    Keywords: Age, error; Age, mineral; Apatite fission track analysis; ELEVATION; Elevation 2; Event label; exhumation; Greater Caucasus; LATITUDE; Latitude 2; Lithology/composition/facies; Location; LONGITUDE; Longitude 2; MS_002_1; MS_002_24; MS_002_50; MS_002_51; MS_003_29; MS_004_3; MS_004_4; MS_004_42c; MS_008_1; MS_011_1; MS_015_1; MS_029_1; MS_040_1; MS_047_1; MS_078_1; MS_092_1; MS_093_1; MS_098_1; MS_146_1; ROCK; Rock sample; Russia; Western Greater Caucasus
    Type: Dataset
    Format: text/tab-separated-values, 66 data points
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  • 10
    Publication Date: 2023-01-13
    Keywords: Angle; Apatite fission track analysis; exhumation; Fission-track length; Greater Caucasus; Identification; MS_002_1; ROCK; Rock sample; Russia; Western Greater Caucasus
    Type: Dataset
    Format: text/tab-separated-values, 6 data points
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