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  • 1
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    Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1 (2018)
    Springer Nature
    Details
    Publication Date: 2018-10-23
    Description: Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1 Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1, Published online: 22 October 2018; doi:10.1038/s41467-018-06854-2 Additional sex combs-like (ASXLs) stimulate BAP1 deubiquitinase activity to induce tumor suppression, but how these complexes work in coordination in vivo is unclear. Here, the authors show the mutually reinforcing roles of BAP1 and ASXLs such that BAP1 promotes DEUBAD monoubiquitination of ASXL2, which in turn stimulates BAP1 DUB activity.
    Electronic ISSN: 2041-1723
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General , Physics
    Published by Springer Nature
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    PAPER CURRENT
  • 2
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    A Multiple Model Based Approach for Deep Space Power System Fault Diagnosis (2019)
    In:  CASI
    Details
    Publication Date: 2019-07-19
    Description: Improving protection and health management capabilities onboard the electrical power system (EPS) for spacecraft is essential for ensuring safe and reliable conditions for deep space human exploration. Electrical protection and control technologies on the National Aeronautics and Space Administration's (NASA's) current human space platform relies heavily on ground support to monitor and diagnose power systems and failures. As communication bandwidth diminishes for deep space applications, a transformation in system monitoring and control becomes necessary to maintain high reliability of electric power service. This paper presents a novel approach for on-line power system security monitoring for autonomous deep space spacecraft.
    Keywords: Spacecraft Propulsion and Power
    Type: GRC-E-DAA-TN63587 , GRC-E-DAA-TN57847 , AIAA SciTech Forum 2019; Jan 07, 2019 - Jan 11, 2019; San Diego, CA; United States
    Format: application/pdf
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    NASA TECHNICAL REPORTS
  • 3
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    An Autonomous Power Controller for the NASA Human Deep Space Gateway (2018)
    In:  CASI
    Details
    Publication Date: 2019-07-13
    Description: Autonomous control of a spacecraft is an enabling technology that must be developed for deep space human exploration. NASA's current long term human space platform, the International Space Station which is in Low Earth Orbit, is in almost continuous communication with ground based mission control. This allows near real-time control of all the vehicle core systems, including power, to be controlled by the ground. As the focus shifts from Low Earth Orbit, communication time-lag and bandwidth limitations beyond geosynchronous orbit does not permit this type of ground based operation. This paper presents the ongoing work at NASA to develop an architecture for autonomous power control system and a vehicle manager which monitors, coordinates, and delegates all the onboard subsystems to enable autonomous control of the complete spacecraft.
    Keywords: Cybernetics, Artificial Intelligence and Robotics
    Type: GRC-E-DAA-TN56670 , International Energy Conversion Engineering Conference; Jul 09, 2018 - Jul 11, 2018; Cincinnati, OH; United States
    Format: application/pdf
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    NASA TECHNICAL REPORTS
  • 4
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    Bifurcation Analysis of DC Electric Power Systems for Deep Space Exploration Spacecraft (2019)
    In:  CASI
    Details
    Publication Date: 2019-07-13
    Description: Electric power system reliability is a crucial factor in the application of both manned and unmanned spacecraft that could alter the success of space exploration missions. Understanding the behavior of these electric systems is essential to determine the safe operating conditions, and subsequently, prevent undesired conditions which may cause system-wide blackouts, leaving the spacecraft in a vulnerable position. This study will use bifurcation analysis to determine the behavior of DC spacecraft electric power systems and identify the major causes of voltage instability.
    Keywords: Spacecraft Propulsion and Power
    Type: GRC-E-DAA-TN65435 , Power and Energy Conference at Illinois (PECI); Feb 28, 2019 - Mar 01, 2019; Champaign, IL; United States
    Format: application/pdf
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    NASA TECHNICAL REPORTS
  • 5
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    A Control Framework for Autonomous Smart Grids for Space Power Applications (2019)
    In:  CASI
    Details
    Publication Date: 2019-11-26
    Description: With the National Aeronautics and Space Administration's (NASA) rising interest in lunar surface operations and deep space exploration, there is a growing need to move from traditional ground-based mission operations to more autonomous vehicle level operations. In lunar surface operations, there are periods of time where communications with ground-based mission control could not occur, forcing vehicles and a lunar base to completely operate independent of the ground. For deep space exploration missions, communication latency times increase to greater than 15 minutes making real-time control of critical systems difficult, if not near impossible. These challenges are driving the need for an autonomous power control system that has the capability to manage power and energy. This will ensure that critical loads have the necessary power to support life systems and carry out critical mission objectives. This paper presents a flexible, hierarchical, distributed control methodology that enables autonomous operation of smart grids and can integrate into a higher level autonomous architecture.
    Keywords: Spacecraft Propulsion and Power
    Type: IAC-19-C3.4.3 , GRC-E-DAA-TN73470 , International Astronautical Congress (IAC); Oct 21, 2019 - Oct 25, 2019; Washington, DC; United States
    Format: application/pdf
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    NASA TECHNICAL REPORTS
  • 6
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    A Control Framework for Autonomous Smart Grids for Space Power Applications (2019)
    In:  CASI
    Details
    Publication Date: 2020-01-04
    Description: With the National Aeronautics and Space Administration's (NASA) rising interest in lunar surface operations and deep space exploration, there is a growing need to move from traditional ground-based mission operations to more autonomous vehicle level operations. In lunar surface operations, there are periods of time where communications with ground-based mission control could not occur, forcing vehicles and a lunar base to completely operate independent of the ground. For deep space exploration missions, communication latency times increase to greater than 15 minutes making real-time control of critical systems difficult, if not near impossible. These challenges are driving the need for an autonomous power control system that has the capability to manage power and energy. This will ensure that critical loads have the necessary power to support life systems and carry out critical mission objectives. This paper presents a flexible, hierarchical, distributed control methodology that enables autonomous operation of smart grids and can integrate into a higher level autonomous architecture.
    Keywords: Spacecraft Propulsion and Power
    Type: GRC-E-DAA-TN73975 , International Astronautical Congress (IAC); Oct 21, 2019 - Oct 25, 2019; Washington, DC; United States
    Format: application/pdf
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    NASA TECHNICAL REPORTS
  • 7
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    Autonomous Power Controller for the NASA Human Deep Space Gateway (2018)
    In:  CASI
    Details
    Publication Date: 2019-07-13
    Description: Autonomous control of a spacecraft is an enabling technology that must be developed for deep space human exploration. NASA's current long term human space platform, the International Space Station which is in Low Earth Orbit, is in almost continuous communication with ground based mission control. This allows near real-time control of all the vehicle core systems, including power, to be controlled by the ground. As the focus shifts from Low Earth Orbit, communication time-lag and bandwidth limitations beyond geosynchronous orbit does not permit this type of ground based operation. This paper presents the ongoing work at NASA to develop an architecture for autonomous power control system and a vehicle manager which monitors, coordinates, and delegates all the onboard subsystems to enable autonomous control of the complete spacecraft.
    Keywords: Spacecraft Instrumentation and Astrionics; Lunar and Planetary Science and Exploration
    Type: GRC-E-DAA-TN58461 , AIAA Propulsion and Energy Forum; Jul 07, 2018 - Jul 13, 2018; Cincinnati, OH; United States
    Format: application/pdf
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    NASA TECHNICAL REPORTS
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